Cervical cancer immunotherapy: facts and hopes
It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …
Current state in the development of candidate therapeutic HPV vaccines
A Yang, J Jeang, K Cheng, T Cheng… - Expert review of …, 2016 - Taylor & Francis
The identification of human papillomavirus (HPV) as an etiological factor for HPV-associated
malignancies creates the opportunity to control these cancers through vaccination …
malignancies creates the opportunity to control these cancers through vaccination …
Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens
M Nakagawa, DP Stites, S Patel… - The Journal of …, 2000 - academic.oup.com
Our cross-sectional study suggested that cytotoxic T lymphocyte (CTL) responses have a
protective effect in squamous intraepithelial lesion (SIL) development. More CTL responses …
protective effect in squamous intraepithelial lesion (SIL) development. More CTL responses …
[HTML][HTML] Perspectives for preventive and therapeutic HPV vaccines
Human Papillomavirus (HPV) has been associated with several human cancers, including
cervical cancer, vulvar cancer, vaginal and anal cancer, and a subset of head and neck …
cervical cancer, vulvar cancer, vaginal and anal cancer, and a subset of head and neck …
Human dendritic cells are activated by chimeric human papillomavirus type-16 virus-like particles and induce epitope-specific human T cell responses in vitro
MP Rudolf, SC Fausch, DM Da Silva… - The Journal of …, 2001 - journals.aai.org
Human papillomavirus (HPV)-derived chimeric virus-like particles (VLPs) are the leading
candidate vaccine for the treatment or prevention of cervical cancer in humans. Dendritic …
candidate vaccine for the treatment or prevention of cervical cancer in humans. Dendritic …
[HTML][HTML] Immunotherapy for cervical cancer: Research status and clinical potential
The high-risk types of human papillomavirus (HPV) have been found to be associated with
most cervical cancers and play an essential role in the pathogenesis of the disease. Despite …
most cervical cancers and play an essential role in the pathogenesis of the disease. Despite …
Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6
M Evans, LK Borysiewicz, AS Evans… - The Journal of …, 2001 - journals.aai.org
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the
development of cervical cancer. The E6 and E7 proteins of HPV are constitutively expressed …
development of cervical cancer. The E6 and E7 proteins of HPV are constitutively expressed …
Vaccination to prevent and treat cervical cancer
Human papillomaviruses (HPVs) are the primary etiologic agents of cervical cancer. Thus,
cervical cancer and other HPV-associated malignancies might be prevented or treated by …
cervical cancer and other HPV-associated malignancies might be prevented or treated by …
The current state of therapeutic and T cell-based vaccines against human papillomaviruses
Human papillomavirus (HPV) is known to be a necessary factor for many gynecologic
malignancies and is also associated with a subset of head and neck malignancies. This …
malignancies and is also associated with a subset of head and neck malignancies. This …
Cervical cancer vaccines: emerging concepts and developments
DM Da Silva, GL Eiben, SC Fausch… - Journal of cellular …, 2001 - Wiley Online Library
Certain human cancers are linked to infection by oncogenic viruses that are able to cause
transformation of the normal host cell into a cancerous cell. Human papillomavirus (HPV) …
transformation of the normal host cell into a cancerous cell. Human papillomavirus (HPV) …