Early in evolution, Ca2+ emerged as the most important second messenger for regulating
widely different cellular functions. In eukaryotic cells Ca2+ signals originate from several …

The importance of Ca2+-signaling for many subcellular processes is well established in
higher eukaryotes, whereas information about protozoa is restricted. Recent genome …

A database search of the Paramecium genome reveals 34 genes related to Ca 2+-release
channels of the inositol-1, 4, 5-trisphosphate (IP 3) or ryanodine receptor type (IP 3 R, RyR) …

Unicellular eukaryotes have been appreciated as model systems for the analysis of crucial
questions in cell and molecular biology. This includes Dictyostelium (chemotaxis, amoeboid …

This special issue of the Journal of Eukaryotic Microbiology (JEM) summarizes
achievements obtained by generations of researchers with ciliates in widely different …

Early in eukaryotic evolution, the cell has evolved a considerable inventory of proteins
engaged in the regulation of intracellular Ca2+ concentrations, not only to avoid toxic effects …

Due to their well-defined pathways of vesicle trafficking and manyfold mutants ciliates have
served as good model systems. Further studies required the development of databases, now …

The aim of the present article is to analyse the evolutionary links between protozoa and
neuronal and neurosecretory cells. To this effect we employ functional and topological data …

The ciliated protozoan, Paramecium tetraurelia has a high basic Ca 2+ leakage rate which is
counteracted mainly by export through a contractile vacuole complex, based on its V-type …

Abstract The genus Tetrahymena (Ciliophora, Oligohymenophorea) probably represents the
best studied ciliate genus. At present, more than forty species have been described. All are …