Endothelial dysfunction in atherosclerotic cardiovascular diseases and beyond: from mechanism to pharmacotherapies

S Xu, I Ilyas, PJ Little, H Li, D Kamato, X Zheng… - Pharmacological …, 2021 - ASPET
The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading
cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen …

Overview of OxLDL and its impact on cardiovascular health: focus on atherosclerosis

AV Poznyak, NG Nikiforov, AM Markin… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular pathologies maintain the leading position in mortality worldwide.
Atherosclerosis is a chronic disease that can result in a variety of serious complications …

Dietary fibre in hypertension and cardiovascular disease management: systematic review and meta-analyses

AN Reynolds, A Akerman, S Kumar, HT Diep Pham… - BMC medicine, 2022 - Springer
Background Higher dietary fibre intakes are associated with a reduced risk of developing
cardiovascular disease (CVD), and increasing intake has been shown to reduce blood …

Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Nrf2 and heme oxygenase-1 involvement in atherosclerosis related oxidative stress

JA Alonso-Piñeiro, A Gonzalez-Rovira… - Antioxidants, 2021 - mdpi.com
Atherosclerosis remains the underlying process responsible for cardiovascular diseases
and the high mortality rates associated. This chronic inflammatory disease progresses with …

Dyslipidemia, diabetes and atherosclerosis: role of inflammation and ROS-redox-sensitive factors

E Hasheminasabgorji, JC Jha - Biomedicines, 2021 - mdpi.com
The prevalence of diabetes is growing at an alarming rate with increased disability,
morbidity, and often premature mortality because of the various complications of this …

Ferroptosis signaling and regulators in atherosclerosis

Y Wang, Y Zhao, T Ye, L Yang, Y Shen… - Frontiers in cell and …, 2021 - frontiersin.org
Atherosclerosis (AS) is a major cause of cardiovascular diseases such as coronary heart
disease, heart failure and stroke. Abnormal lipid metabolism, oxidative stress and …

Inflammation, oxidative stress, senescence in atherosclerosis: thioredoxine-1 as an emerging therapeutic target

K El Hadri, R Smith, E Duplus, C El Amri - International journal of …, 2021 - mdpi.com
Atherosclerosis is a leading cause of cardiovascular diseases (CVD) worldwide and
intimately linked to aging. This pathology is characterized by chronic inflammation, oxidative …

Functional ingredients from agri-food waste: Effect of inclusion thereof on phenolic compound content and bioaccessibility in bakery products

V Melini, F Melini, F Luziatelli, M Ruzzi - Antioxidants, 2020 - mdpi.com
Reducing food loss and waste is among the efforts to relieve the pressure on natural
resources and move towards more sustainable food systems. Alternative pathways of food …