p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression
A Kourtidis, SP Ngok, PZ Anastasiadis - Progress in molecular biology and …, 2013 - Elsevier
Abstract p120 catenin is the best studied member of a subfamily of proteins that associate
with the cadherin juxtamembrane domain to suppress cadherin endocytosis. p120 also …
with the cadherin juxtamembrane domain to suppress cadherin endocytosis. p120 also …
Dynamics and regulation of epithelial adherens junctions: recent discoveries and controversies
AI Ivanov, NG Naydenov - International review of cell and molecular …, 2013 - Elsevier
Adherens junctions (AJs) are evolutionarily conserved plasma-membrane structures that
mediate cell–cell adhesions in multicellular organisms. They are organized by several types …
mediate cell–cell adhesions in multicellular organisms. They are organized by several types …
p120-catenin in cancer–mechanisms, models and opportunities for intervention
RCJ Schackmann, M Tenhagen… - Journal of cell …, 2013 - journals.biologists.com
The epithelial adherens junction is an E-cadherin-based complex that controls tissue
integrity and is stabilized at the plasma membrane by p120-catenin (p120, also known as …
integrity and is stabilized at the plasma membrane by p120-catenin (p120, also known as …
Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases
LR Lessey, SC Robinson, R Chaudhary… - Frontiers in Cell and …, 2022 - frontiersin.org
The function and structure of the mammalian epithelial cell layer is maintained by distinct
intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and …
intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and …
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability
N Zebda, Y Tian, X Tian, G Gawlak… - Journal of Biological …, 2013 - ASBMB
p120-catenin is a multidomain intracellular protein, which mediates a number of cellular
functions, including stabilization of cell-cell transmembrane cadherin complexes as well as …
functions, including stabilization of cell-cell transmembrane cadherin complexes as well as …
Cadherins and catenins in cancer: connecting cancer pathways and tumor microenvironment
WH Lin, LM Cooper, PZ Anastasiadis - Frontiers in Cell and …, 2023 - frontiersin.org
Cadherin-catenin complexes are integral components of the adherens junctions crucial for
cell-cell adhesion and tissue homeostasis. Dysregulation of these complexes is linked to …
cell-cell adhesion and tissue homeostasis. Dysregulation of these complexes is linked to …
E-cadherin activating antibodies limit barrier dysfunction and inflammation in mouse inflammatory bowel disease
C Bandyopadhyay, L Schecterson, BM Gumbiner - Tissue Barriers, 2021 - Taylor & Francis
Deficits in gastrointestinal (GI) paracellular permeability has been implicated in etiology of
Inflammatory Bowel Disease (IBD), and E-cadherin, a key component of the epithelial …
Inflammatory Bowel Disease (IBD), and E-cadherin, a key component of the epithelial …
Adherens junctions and cancer
V Vasioukhin - Adherens junctions: from molecular mechanisms to …, 2012 - Springer
Cadherins and catenins are the central cell–cell adhesion molecules in adherens junctions
(AJs). This chapter reviews the knowledge concerning the role of cadherins and catenins in …
(AJs). This chapter reviews the knowledge concerning the role of cadherins and catenins in …
Nuclear Kaiso expression is associated with high grade and triple-negative invasive breast cancer
JF Vermeulen, RAH van de Ven, C Ercan… - PloS one, 2012 - journals.plos.org
Kaiso is a BTB/POZ transcription factor that is ubiquitously expressed in multiple cell types
and functions as a transcriptional repressor and activator. Little is known about Kaiso …
and functions as a transcriptional repressor and activator. Little is known about Kaiso …
Dancing from bottoms up–roles of the POZ-ZF transcription factor Kaiso in cancer
The POZ-ZF transcription factor Kaiso was discovered two decades ago as a binding partner
for p120 ctn. Since its discovery, roles for Kaiso in diverse biological processes (epithelial-to …
for p120 ctn. Since its discovery, roles for Kaiso in diverse biological processes (epithelial-to …