Death from sepsis in the neonatal period remains a serious threat for millions. Within 3 days
of administration, bacille Calmette-Guérin (BCG) vaccination can reduce mortality from …

Respiratory muscle dysfunction is a cardinal feature of acute and chronic respiratory failure
in COPD. Diaphragm and accessory inspiratory muscles face increased load due to …

Adult regenerative myogenesis is vital for restoring normal tissue structure after muscle
injury. Muscle regeneration is dependent on progenitor satellite cells, which proliferate in …

Background: Diaphragm and psoas are affected during sepsis in animal models. Whether
diaphragm or limb muscle is preferentially affected during sepsis in the critically ill remains …

Background Mechanical ventilation (MV) is a life-saving technology that restores or assists
breathing. Like any treatment, MV has side effects. In some patients it can cause …

Objective: Diaphragmatic weakness and acute respiratory failure are common in sepsis.
Nuclear factor-κB acts as a general coordinator of the systemic inflammatory response, but …

Mitochondrial dysfunction plays an important role in the pathogenesis of diaphragm
weakness during sepsis. Recently, hydrogen sulfide (H 2 S), a gaseous transmitter …

The C–C chemokine receptors (CCRs) family is involved in diverse pathophysiological
processes in mammals, such as immune regulation and cancer, but their functions in …

Chronic liver diseases are a group of pathologies affecting the liver with high prevalence
worldwide. Among them, cholestatic chronic liver diseases (CCLD) are characterized by …

Exercise-induced muscle injury and the subsequent release of Damage-Associated
Molecular Patterns (DAMP) result in soreness and inflammation. Dietary supplements may …