Importance Animal studies have found that antenatal corticosteroids affect many organs
across multiple stages of life. However, the long-term outcomes in human children are not …

In multicellular organisms, development is based in part on the integration of communication
systems. Two neuroendocrine axes, the hypothalamic–pituitary–thyroid and the …

A course of antenatal corticosteroids given within the seven days prior to preterm birth
reduces perinatal and neonatal death and respiratory distress syndrome.[Grade A] For …

Blockade of the interleukin-1 (IL-1) pathway has been used therapeutically in several
inflammatory diseases including arthritis and cryopyrin-associated periodic syndrome …

Placental protein 13 (PP13) is a regulatory protein involved in remodeling the vascular
system of the pregnancy and extending the immune tolerance of the mother to the growing …

Objectives The objective of this study was to use modern analysis and reporting methods to
present the full results of the first randomized trial of antenatal corticosteroids, performed 50 …

Previously, we demonstrated in pigs that renal denervation halves glucose release during
hypoglycaemia and that a prenatal dexamethasone injection caused increased ACTH and …

A wealth of innate and adaptive immune cells and hormones are involved in mounting
tolerance towards the fetus, a key aspect of successful reproduction. We could recently show …

Bronchopulmonary dysplasia (BPD) is the most significant respiratory complication of
prematurity, and its consequences last from birth into adulthood. Unfortunately, the dramatic …

While the effect of antenatally administered corticosteroids on fetal heart rate (HR) and heart
rate variability (HRV) is well established, little information is available on how these drugs …