Abstract Three-dimensional (3D) printing is revolutionising the way that medicines are
manufactured today, paving the way towards more personalised medicine. However, there …

Liquid–liquid phase separation (LLPS) in macromolecular solutions (eg, coacervation) is
relevant both to technology and to the process of mesoscale structure formation in cells. The …

In this work, a machine learning (ML)-approach was developed to predict pure-component
parameters for the Perturbed-Chain Statistical Associating Fluid Theory (PC-SAFT) for non …

Different from previously reported co-amorphous systems, a co-amorphous curcumin-
magnolol (CUR-MAG CM) system, as compared with its crystalline counterparts, exhibited …

This paper reviews the structure and properties of amorphous active pharmaceutical
ingredients (APIs), including small molecules and proteins, in the glassy state (below the …

A current trend in the development of amorphous solid dispersions (ASDs) is the
combination of two polymers for synergistic enhancement in supersaturation of poorly …

This review provides a comprehensive overview of additive manufacturing (AM) or 3D-
printing (3DP) applications in the pharmaceutical industry, with a particular focus on the …

As performance of ternary amorphous solid dispersions (ASDs) depends on the solid-state
characteristics and polymer mixing, a comprehensive understanding of synergistic …

One way to increase the slow dissolution rate and the associated low bioavailability of newly
developed active pharmaceutical ingredients (APIs) is to dissolve the API in a polymer …

During the dissolution of amorphous solid dispersion (ASD) formulations, the gel layer that
forms at the ASD/water interface strongly dictates the release of the active pharmaceutical …