PGC-1α affects skeletal muscle and adipose tissue development by regulating mitochondrial biogenesis
S Kong, B Cai, Q Nie - Molecular Genetics and Genomics, 2022 - Springer
The discovery and interpretation of peroxisome proliferator-activated receptor γ coactivator
1α (PGC-1α) protein in mitochondrial biogenesis, skeletal muscle and adipose tissue …
1α (PGC-1α) protein in mitochondrial biogenesis, skeletal muscle and adipose tissue …
Role of SERCA and sarcolipin in adaptive muscle remodeling
PJ Chambers, ES Juracic… - American Journal of …, 2022 - journals.physiology.org
Sarcolipin (SLN) is a small regulatory protein that inhibits the sarco (endo) plasmic reticulum
Ca2+-ATPase (SERCA) pump. When bound to SERCA, SLN reduces the apparent Ca2+ …
Ca2+-ATPase (SERCA) pump. When bound to SERCA, SLN reduces the apparent Ca2+ …
iPADD: a computational tool for predicting potential antidiabetic drugs using machine learning algorithms
XW Liu, TY Shi, D Gao, CY Ma, H Lin… - Journal of Chemical …, 2023 - ACS Publications
Diabetes mellitus is a chronic metabolic disease, which causes an imbalance in blood
glucose homeostasis and further leads to severe complications. With the increasing …
glucose homeostasis and further leads to severe complications. With the increasing …
Relieving cellular energy stress in aging, neurodegenerative, and metabolic diseases, SIRT1 as a therapeutic and promising node
Y Fang, X Wang, D Yang, Y Lu, G Wei, W Yu… - Frontiers in Aging …, 2021 - frontiersin.org
The intracellular energy state will alter under the influence of physiological or pathological
stimuli. In response to this change, cells usually mobilize various molecules and their …
stimuli. In response to this change, cells usually mobilize various molecules and their …
Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel …
S Spinelli, L Guida, M Passalacqua, M Magnone… - Antioxidants, 2023 - mdpi.com
The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors
LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO …
LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO …
The ABA-LANCL1/2 Hormone-Receptors System Protects H9c2 Cardiomyocytes from Hypoxia-Induced Mitochondrial Injury via an AMPK-and NO-Mediated …
S Spinelli, L Guida, T Vigliarolo, M Passalacqua… - Cells, 2022 - mdpi.com
Abscisic acid (ABA) regulates plant responses to stress, partly via NO. In mammals, ABA
stimulates NO production by innate immune cells and keratinocytes, glucose uptake and …
stimulates NO production by innate immune cells and keratinocytes, glucose uptake and …
Kinase CIPK9 integrates glucose and abscisic acid signaling to regulate seed oil metabolism in rapeseed
N Wang, B Tao, J Mai, Y Guo, R Li, R Chen… - Plant …, 2023 - academic.oup.com
Rapeseed (Brassica napus), an important oil crop worldwide, provides large amounts of
lipids for human requirements. Calcineurin B-like (CBL)-interacting protein kinase 9 (CIPK9) …
lipids for human requirements. Calcineurin B-like (CBL)-interacting protein kinase 9 (CIPK9) …
New Insights into the LANCL2-ABA Binding Mode towards the Evaluation of New LANCL Agonists
N Scarano, F Di Palma, N Origlia, F Musumeci… - Pharmaceutics, 2023 - mdpi.com
The lanthionine synthetase C-like (LANCL) proteins include LANCL2, which is expressed in
the central nervous system (CNS) and in peripheral tissues. LANCL2 exhibits …
the central nervous system (CNS) and in peripheral tissues. LANCL2 exhibits …
Inducible deletion of raptor and mTOR from adult skeletal muscle impairs muscle contractility and relaxation
M Baraldo, S Zorzato, AHT Dondjang… - The Journal of …, 2022 - Wiley Online Library
Skeletal muscle weakness has been associated with different pathological conditions,
including sarcopenia and muscular dystrophy, and is accompanied by altered mammalian …
including sarcopenia and muscular dystrophy, and is accompanied by altered mammalian …
Histone deacetylase functions and therapeutic implications for adult skeletal muscle metabolism
S Molinari, C Imbriano, V Moresi, A Renzini… - Frontiers in Molecular …, 2023 - frontiersin.org
Skeletal muscle is a highly adaptive organ that sustains continuous metabolic changes in
response to different functional demands. Healthy skeletal muscle can adjust fuel utilization …
response to different functional demands. Healthy skeletal muscle can adjust fuel utilization …