Background The current review broadly summarises the evidence base for
pharmacotherapies and adjunctive and alternative therapies in the treatment of eating …

Anorexia nervosa is an eating disorder characterized by restrictive eating and an intense
fear of gaining weight. It is a disease with an increasing incidence during the last few …

Objective Growth differentiation factor (GDF)-15 is implicated in regulation of metabolism
and circulating GDF15 increases in response to exercise. The source and regulation of the …

Crosstalk among organs/tissues is important for regulating systemic metabolism. Here, we
demonstrate inter-organ crosstalk between hepatic insulin and hypothalamic leptin actions …

Obesity and eating disorders are conditions that involve eating behaviors and are
sometimes comorbid. Current evidence supports alterations in immunoinflammatory …

Abstract Mammalian sirtuins (SIRT1–7) are members of the nicotine adenine dinucleotide
(NAD+)-dependent family of enzymes critical for histone deacetylation and posttranslational …

Anorexia nervosa (AN) represents a disorder with the highest mortality rate among all
psychiatric diseases, yet our understanding of its pathophysiological components continues …

It has been hypothesized that leptin level alterations in Eating Disorders (EDs) represent a
maintaining factor for pathological reward-related ED behaviors, given leptin role in the …

Background Preeclampsia represents a major pregnancy complication, associated with high
rates of perinatal morbidity. The aim of this systematic review is to accumulate current …

Based on the recent observation that human recombinant leptin (r‐Met‐hu‐leptin;
metreleptin) may induce a profound alleviation of the complex symptomatology of patients …