Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
Cell death is a fundamental biological phenomenon that is essential for the survival and
development of an organism. Emerging evidence also indicates that cell death contributes to …
development of an organism. Emerging evidence also indicates that cell death contributes to …
Cutaneous leishmaniasis: immune responses in protection and pathogenesis
Cutaneous leishmaniasis is a major public health problem and causes a range of diseases
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …
Immune responses in leishmaniasis: an overview
AC Costa-da-Silva, DO Nascimento… - Tropical medicine and …, 2022 - mdpi.com
Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90
countries in the world. More than 20 Leishmania species cause different forms of …
countries in the world. More than 20 Leishmania species cause different forms of …
How to master the host immune system? Leishmania parasites have the solutions!
M Rossi, N Fasel - International immunology, 2018 - academic.oup.com
Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
Tuberculosis is the leading cause of death by an infectious disease worldwide. However, the
involvement of innate lymphoid cells (ILCs) in immune responses to infection with …
involvement of innate lymphoid cells (ILCs) in immune responses to infection with …
Pro-and anti-inflammatory cytokines in cutaneous leishmaniasis: a review
Cutaneous leishmaniasis (CL) is caused by different species of the genus Leishmania. Pro-
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …
Cytosolic recognition of microbes and pathogens: inflammasomes in action
Infection is a dynamic biological process underpinned by a complex interplay between the
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …
Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses
KD Mayer-Barber, B Yan - Cellular & molecular immunology, 2017 - nature.com
Over the past decades the notion of 'inflammation'has been extended beyond the original
hallmarks of rubor (redness), calor (heat), tumor (swelling) and dolor (pain) described by …
hallmarks of rubor (redness), calor (heat), tumor (swelling) and dolor (pain) described by …
Gut microbes egested during bites of infected sand flies augment severity of leishmaniasis via inflammasome-derived IL-1β
R Dey, AB Joshi, F Oliveira, L Pereira… - Cell host & …, 2018 - cell.com
Leishmania donovani parasites are the cause of visceral leishmaniasis and are transmitted
by bites from phlebotomine sand flies. A prominent feature of vector-transmitted Leishmania …
by bites from phlebotomine sand flies. A prominent feature of vector-transmitted Leishmania …
[HTML][HTML] Macrophages as host, effector and immunoregulatory cells in leishmaniasis: Impact of tissue micro-environment and metabolism
C Bogdan - Cytokine: X, 2020 - Elsevier
Leishmania are protozoan parasites that predominantly reside in myeloid cells within their
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …