The implications of zinc therapy in combating the COVID-19 global pandemic

N Samad, TE Sodunke, AR Abubakar… - Journal of …, 2021 - Taylor & Francis
The global pandemic from COVID-19 infection has generated significant public health
concerns, both health-wise and economically. There is no specific pharmacological antiviral …

[HTML][HTML] Role of the renin–angiotensin–aldosterone and kinin–kallikrein systems in the cardiovascular complications of COVID-19 and long COVID

SL Cooper, E Boyle, SR Jefferson, CRA Heslop… - International Journal of …, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus responsible
for the COVID-19 pandemic. Patients may present as asymptomatic or demonstrate mild to …

European Resuscitation Council Guidelines 2021: cardiac arrest in special circumstances

C Lott, A Truhlář, A Alfonzo, A Barelli… - Resuscitation, 2021 - Elsevier
Abstract These European Resuscitation Council (ERC) Cardiac Arrest in Special
Circumstances guidelines are based on the 2020 International Consensus on …

A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm

MR Garvin, C Alvarez, JI Miller, ET Prates, AM Walker… - elife, 2020 - elifesciences.org
Neither the disease mechanism nor treatments for COVID-19 are currently known. Here, we
present a novel molecular mechanism for COVID-19 that provides therapeutic intervention …

Management of ventricular electrical storm: a contemporary appraisal

GN Kowlgi, YM Cha - EP Europace, 2020 - academic.oup.com
Ventricular electrical storm (VES) is a clinical scenario characterized by the clustering of
multiple episodes of sustained ventricular arrhythmias (VA) over a short duration. Patients …

Finerenone and effects on mortality in chronic kidney disease and type 2 diabetes: a FIDELITY analysis

G Filippatos, SD Anker, P August… - European Heart …, 2023 - academic.oup.com
Aims Finerenone reduces the risk of cardiovascular events in patients with chronic kidney
disease (CKD) and type 2 diabetes (T2D). We investigated the causes of mortality in the …

Sodium and potassium changes during decongestion with acetazolamide–A pre‐specified analysis from the ADVOR trial

S Dhont, P Martens, E Meekers, J Dauw… - European Journal of …, 2023 - Wiley Online Library
Aims Acetazolamide, an inhibitor of proximal tubular sodium reabsorption, leads to more
effective decongestion in acute heart failure (AHF). It is unknown whether acetazolamide …

[PDF][PDF] Hypokalemia promotes arrhythmia by distinct mechanisms in atrial and ventricular myocytes

K Tazmini, M Frisk, M Laasmaa, A Lewalle, S Morotti… - Biophysical …, 2020 - cell.com
Methods: We used in vivo ECG telemetry of control mice and mice that harbor an LQT3-
causing mutation (Scn5aDKPQ/+). All animals were genetically engineered to enable us to …

Repurposed drugs, molecular vaccines, immune‐modulators, and nanotherapeutics to treat and prevent COVID‐19 associated with SARS‐CoV‐2, a deadly …

T Dube, A Ghosh, J Mishra, UB Kompella… - Advanced …, 2021 - Wiley Online Library
The deadly pandemic, coronavirus disease 2019 (COVID‐19), caused due to the severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has paralyzed the world …

Prediction of arrhythmia susceptibility through mathematical modeling and machine learning

M Varshneya, X Mei, EA Sobie - Proceedings of the …, 2021 - National Acad Sciences
At present, the QT interval on the electrocardiographic (ECG) waveform is the most common
metric for assessing an individual's susceptibility to ventricular arrhythmias, with a long QT …