Background: Sleep disturbance and deficiency are common among older adults and have
been linked with dementia and all-cause mortality. Using nationally representative data, we …

Suboptimal sleep causes cognitive decline and probably accelerates Alzheimer's Disease
(AD) progression. Several sleep interventions have been tested in established AD dementia …

Sleep is vital and universal across all species studied, and lack of sleep has detrimental
consequences for the organism. A broadly accepted theory for the purpose of sleep has yet …

Sleep disorders are prevalent in Alzheimer's disease (AD) and a major cause of
institutionalization. Like AD pathology, sleep abnormalities can appear years before …

Recent evidence has advanced our understanding of the function of sleep to include
removal of neurotoxic protein aggregates via the glymphatic system. However, most …

Recent studies in mouse models of Alzheimer's disease (AD) and in humans suggest that
sleep disruption and amyloid-beta (Aβ) accumulation are interrelated, and may, thus …

Abstract Study Objectives To determine the effect of self-reported clinical diagnosis of
obstructive sleep apnea (OSA) on longitudinal changes in brain amyloid PET and CSF …

Abstract Study Objectives: To investigate the contribution of sleep duration and quality to
age-related changes in brain structure and cognitive performance in relatively healthy older …

A substantial body of research now implicates the circadian clock in the regulation of an
array of diverse biological processes including glial function, metabolism, peripheral …

Background Emerging data suggest an important relationship between sleep and
Alzheimer's disease (AD), but how poor sleep promotes the development of AD remains …