Background Fabry disease, an inherited lysosomal storage disorder, causes multi-organ
pathology resulting in substantial morbidity and a reduced life expectancy. Although Fabry …

Abstract Small-fibre neuropathy (SFN), a disorder of thinly myelinated Aδ-fibres and
unmyelinated C-fibres, is clinically characterized by neuropathic pain symptoms and …

Patients with Fabry disease (FD) are at a high risk for developing chronic kidney disease
and cardiovascular disease. The availability of specific but costly therapy has elevated the …

Fabry disease is an inherited X-linked disorder that presents during childhood in male and
female patients. Young patients may initially experience pain, hypohidrosis, and …

Fabry disease is a frequent lysosomal storage disorder secondary to the deficiency of alpha-
galactosidase A enzyme. This X-linked genetic disease realizes progressive and systemic …

Corneal confocal microscopy is a non‐invasive ophthalmic imaging modality, which was
initially used for the diagnosis and management of corneal diseases. However, over the last …

Summary Aims Patients with Fabry disease (FD) characteristically develop peripheral
neuropathy at an early age, with pain being a crucial symptom of underlying pathology …

Fabry disease (FD) is an X-linked lysosomal storage disorder caused by absence or
deficient activity of α-galactosidase A (α-Gal A) due to mutations in the α-galactosidase A …

SFN represents a distinct condition encountered in patients with different acquired and
genetic disorders. The recent improved definition of clinical and skin biopsy criteria allows …

Purpose: Fabry disease is a pan-ethnic, progressive, X-linked genetic disorder that
commonly presents in childhood and is caused by deficient activity of the lysosomal enzyme …