The pharmacology and pharmacokinetics of drospirenone, a unique progestogen, are
reviewed in this paper. Unlike other progestogens, drospirenone, an analogue of …

Menstrually related symptoms and disorders are multidimensional and affect diverse
physiologic systems. Elucidation of the pathophysiologic mechanisms of these disorders …

The leading reference in reproductive health for 30 years, with over 2,000,000 copies in
print, Contraceptive Technology is included on CD-ROM with all copies of the book and also …

Severe premenstrual syndrome (PMS) and, more recently, premenstrual dysphoric disorder
(PMDD) have been studied extensively over the last 20 years. The defining criteria for …

Background Concern about estrogen‐related adverse effects has led to progressive
reductions in the estrogen dose in combination oral contraceptives (COCs). However …

The spironolactone derivative drospirenone is combined with ethinylestradiol or estetrol in
combined oral contraceptives. Formulations with 17-β-estradiol are used to treat climacteric …

The aim of this study was to investigate the effects of the new estro-progestinic containing
the antimineralcorticoid progestogen drospirenone (DRSP) in women with polycystic ovary …

Progesterone is more than a progestin. Beyond functions in cycle and pregnancy,
progesterone binds with high affinity to the mineralocorticoid receptor (MR) acting as an …

Hyperinsulinemic hyperandrogenism with anovulation, the so-called polycystic ovary
syndrome (PCOS), is the most frequent endocrine disorder of young women. One of the …

In spite of combined oral contraceptives (COCs) having been available for more than 50
years, surprisingly little is known about the prevalence of truly COC‐related adverse mood …