Current therapies for relapsed/refractory (R/R) pediatric myeloid neoplasms are
inadequately effective. Real‐world data (RWD) can improve care by augmenting traditional …

Abstract Treatment of metastatic non-small cell lung cancer (mNSCLC) has been modified
due to the development of immunotherapy. We assessed survival outcomes (overall [OS] …

Objective To provide recommendations for overcoming the challenges associated with the
generation and use of real-world evidence (RWE) in regulatory approvals, health technology …

Real world data (RWD) and real-world evidence (RWE) plays an increasingly important role
in clinical research since scientific knowledge is obtained during routine clinical large-scale …

In recent years, regulatory bodies have increasingly recognized the utility of real-world
evidence (RWE) for supplementing and supporting clinical trial data in new drug …

Objective Traditionally, validation of surrogate endpoints has been carried out using
randomized controlled trial (RCT) data. However, RCT data may be too limited to validate …

The value and future potentials of AI in healthcare are becoming self-evident, presenting an
escalating body of evidence. However, the adoption into clinical practice is still significantly …

Growing awareness of the genetic basis of disease is transforming the opportunities for
improving patient care by accelerating the development, delivery and uptake of …

Regulators and Health Technology Assessment (HTA) bodies are increasingly familiar with,
and publishing guidance on, external controls derived from real‐world data (RWD) to …

Objective: To evaluate the real-world efficacy, safety, and functional outcomes of PRC-063
(multilayer-release methylphenidate) versus lisdexamfetamine (LDX) in ADHD subjects in a …