Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …

Exacerbations of chronic obstructive pulmonary disease (COPD) are important events that
carry significant consequences for patients. Some patients experience frequent …

Background We evaluated the effect of dual, longacting inhaled bronchodilator treatment on
exacerbations in patients with severe and very severe chronic obstructive pulmonary …

Background Pulmonary hyperinflation in chronic obstructive pulmonary disease (COPD) is
associated with reduced biventricular end-diastolic volumes and increased morbidity and …

Background We compared the efficacy and safety of indacaterol and tiotropium in patients
with severe chronic obstructive pulmonary disease (COPD) and a history of at least one …

Background Randomized controlled trials (RCTs) indicate that long-acting bronchodilator
combinations, such as β2-agonist (LABA)/muscarinic antagonist (LAMA), have favorable …

Background Epidemiological studies have shown an increase in morbidity and mortality
rates in patients with chronic obstructive pulmonary disease (COPD) following exposure to …

Asthma and chronic obstructive pulmonary disease (COPD) have both been historically
associated with significant morbidity and financial burden. These diseases can be induced …

Asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis are
representative chronic respiratory diseases (CRDs). Although they differ in terms of disease …

The main complaint of patients with chronic obstructive pulmonary disease (COPD) is
shortness of breath with exercise, that is usually progressive. The principal mechanism that …