Smart chemistry for traceless release of anticancer therapeutics
In the design of delivery strategies for anticancer therapeutics, the controlled release of
intact cargo at the destined tumor and metastasis locations is of particular importance. To …
intact cargo at the destined tumor and metastasis locations is of particular importance. To …
Liquid-phase separations coupled with ion mobility-mass spectrometry for next-generation biopharmaceutical analysis
DM Makey, BT Ruotolo - Expert Review of Proteomics, 2024 - Taylor & Francis
Introduction The pharmaceutical industry continues to expand its search for innovative
biotherapeutics. The comprehensive characterization of such therapeutics requires many …
biotherapeutics. The comprehensive characterization of such therapeutics requires many …
Eukaryotic translation initiation factor 2α kinase 2 in pancreatic cancer: An approach towards managing clinical prognosis and molecular immunological …
HX Du, H Wang, XP Ma, H Chen… - Oncology …, 2023 - spandidos-publications.com
Most patients with pancreatic cancer are already in the late stages of the disease when they
are diagnosed, and pancreatic cancer is a deadly disease with a poor prognosis. With the …
are diagnosed, and pancreatic cancer is a deadly disease with a poor prognosis. With the …
Morchella conica, Morchella esculenta and Morchella delicosa Induce Apoptosis in Breast and Colon Cancer Cell Lines via Pro-apoptotic and Anti-apoptotic …
Objective To explore the potential apoptotic mechanisms of 3 Morchella extracts (Morchella
conica, Morchella esculenta and Morchella delicosa) on breast and colon cancer cell lines …
conica, Morchella esculenta and Morchella delicosa) on breast and colon cancer cell lines …
[HTML][HTML] Charge-guided masking of a membrane-destabilizing peptide enables efficient endosomal escape for targeted intracellular delivery of proteins
Y Zhao, H Jiang, H Chen, J Yu, L Wang, W Zhou… - … Pharmaceutica Sinica B, 2024 - Elsevier
Intracellular delivery of biologicals such as peptides, proteins, and nucleic acids presents a
great opportunity for innovative therapeutics. However, the endosome entrapment remains a …
great opportunity for innovative therapeutics. However, the endosome entrapment remains a …
[PDF][PDF] Revolutionizing Medicine: Breakthrough Cell-Based Delivery System for Targeted Therapy Unveiled.
R Solofondrazaintsoanirina - 2023 - hcommons.org
The global burden of cancer remains high, with tens of millions of new cases being
diagnosed and millions of lives being lost to the disease each year. Chemotherapy and …
diagnosed and millions of lives being lost to the disease each year. Chemotherapy and …