Chronic obstructive pulmonary disease (COPD) is a devastating lung disease with a high
personal and societal burden. Exposure to toxic particles and gases, including cigarette …

Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …

The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Rationale: Deep learning is a powerful tool that may allow for improved outcome prediction.
Objectives: To determine if deep learning, specifically convolutional neural network (CNN) …

Background The concept that small conducting airways less than 2 mm in diameter become
the major site of airflow obstruction in chronic obstructive pulmonary disease (COPD) is well …

Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

Background The coexistence of COPD and asthma is widely recognized but has not been
well described. This study characterizes clinical features, spirometry, and chest CT scans of …

OBJECTIVE. This study evaluates the relationships between quantitative CT (QCT) and
spirometric measurements of disease severity in cigarette smokers with and without chronic …

The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …

The small airways are defined as those less than 2 mm in diameter. They are a major site of
pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) …