[HTML][HTML] Application of intranasal administration in the delivery of antidepressant active ingredients

Z Jin, Y Han, D Zhang, Z Li, Y Jing, B Hu, S Sun - Pharmaceutics, 2022 - mdpi.com
As a mental disease in modern society, depression shows an increasing occurrence, with
low cure rate and high recurrence rate. It has become the most disabling disease in the …

[HTML][HTML] Autophagy: an important target for natural products in the treatment of bone metabolic diseases

Z Li, D Li, H Su, H Xue, G Tan, Z Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Bone homeostasis depends on a precise dynamic balance between bone resorption and
bone formation, involving a series of complex and highly regulated steps. Any imbalance in …

Berberine attenuates depression-like behavior by modulating the hippocampal NLRP3 ubiquitination signaling pathway through Trim65

L Yang, Y Huang, F Chen, Y Wang, K Su… - International …, 2023 - Elsevier
Objective Increasing evidence suggests that inflammation appears to play a role in the
genesis of depression. Berberine has potent anti-inflammatory effects and potential …

[HTML][HTML] Comparison of the protective effects of CS/TPP and CS/HPMCP nanoparticles containing berberine in ethanol-induced hepatotoxicity in rat

M Mahboubi Kancha, M Alizadeh… - … Medicine and Therapies, 2024 - Springer
Background Alcoholic liver disease (ALD) is a globally critical condition with no available
efficient treatments. Methods Herein, we generated chitosan (CS) nanoparticles cross-linked …

Design, synthesis and biological evaluation of novel 9-N-substituted-13-alkylberberine derivatives from Chinese medicine as anti-hepatocellular carcinoma agents

J Chen, Y Duan, K Yang, J Wang, J Yan, C Gu… - Bioorganic & Medicinal …, 2023 - Elsevier
A series of novel 9-N-substituted-13-alkylberberine derivatives from Chinese medicine were
designed and synthesized with improved anti-hepatocellular carcinoma (HCC) activities …

[HTML][HTML] NADPH-oxidases as potential pharmacological targets for thrombosis and depression comorbidity

P Amadio, L Sandrini, M Zarà, SS Barbieri, A Ieraci - Redox Biology, 2024 - Elsevier
There is a complex interrelationship between the nervous system and the cardiovascular
system. Comorbidities of cardiovascular diseases (CVD) with mental disorders, and vice …

Argemone mexicana L. (Papaveraceae): chemistry, pharmacology, and toxicology

J Patocka, M Ovando-Martinez, Z Navratilova… - Phytochemistry …, 2024 - Springer
This mini-review is a compilation of research data on the phytochemistry, pharmacology,
and various therapeutic potentials of Argemone mexicana. A. mexicana is a well-known …

PLANT PIGMENTS IN PSYCHIATRY AND NEUROLOGY: HISTORICAL AND MODERN USES. PART II. A LITERATURE REVIEW WITH A CLINICAL CASE …

RA Bekker, YV Bykov - Siberian Journal of Life Sciences and …, 2023 - discover-journal.ru
Purpose. To continue the narrative that we have started in the first part of this article, telling
the reader about the history of the use of certain plant pigments in the treatment of several …

[PDF][PDF] Application of Intranasal Administration in the Delivery of Antidepressant Active Ingredients. Pharmaceutics 2022, 14, 2070

Z Jin, Y Han, D Zhang, Z Li, Y Jing, B Hu, S Sun - 2022 - pdfs.semanticscholar.org
As a mental disease in modern society, depression shows an increasing occurrence, with
low cure rate and high recurrence rate. It has become the most disabling disease in the …