Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology

S Wahab, S Annadurai, SS Abullais, G Das, W Ahmad… - Plants, 2021 - mdpi.com
There are more than 30 species of Glycyrrhiza genus extensively spread worldwide. It was
the most prescribed herb in Ancient Egyptian, Roman, Greek, East China, and the West from …

A review of the pharmacological efficacy and safety of licorice root from corroborative clinical trial findings

YJ Kwon, DH Son, TH Chung, YJ Lee - Journal of medicinal food, 2020 - liebertpub.com
Since ancient times, licorice, the root of Glycyrrhiza glabra, has been known to have a wide
spectrum of therapeutic effects. Glycyrrhizin is cleaved to glycyrrhizic acid, which is …

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation

B Bengsch, B Seigel, M Ruhl, J Timm, M Kuntz… - PLoS …, 2010 - journals.plos.org
Exhausted CD8+ T cell responses during chronic viral infections are defined by a complex
expression pattern of inhibitory receptors. However, very little information is currently …

Restoration of HCV-specific CD8+ T cell function by interferon-free therapy

B Martin, N Hennecke, V Lohmann, A Kayser… - Journal of …, 2014 - Elsevier
Background & Aims Chronic hepatitis C virus (HCV) infection is characterised by a failure of
virus-specific CD8+ T cells that is mainly caused by viral escape and T cell exhaustion …

Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

J Schulze zur Wiesch, D Ciuffreda… - Journal of Experimental …, 2012 - rupress.org
Vigorous proliferative CD4+ T cell responses are the hallmark of spontaneous clearance of
acute hepatitis C virus (HCV) infection, whereas comparable responses are absent in …

HIV and co‐infections

CC Chang, M Crane, JL Zhou, M Mina… - Immunological …, 2013 - Wiley Online Library
Despite significant reductions in morbidity and mortality secondary to availability of effective
combination anti‐retroviral therapy (cART), human immunodeficiency virus (HIV) infection …

Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy

CM Lange, J Bojunga, E Ramos-Lopez… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Vitamin D is an important immune modulator and preliminary data
indicated an association between vitamin D deficiency and sustained virologic response …

[HTML][HTML] T cell immunity to hepatitis C virus: Lessons for a prophylactic vaccine

R Thimme - Journal of hepatology, 2021 - Elsevier
There is consensus that hepatitis C virus-specific T cells play a central role in the outcome,
clearance versus persistence, of acute infection and that they contribute to protection against …

Therapy implications of hepatitis C virus genetic diversity

MA Martinez, S Franco - Viruses, 2020 - mdpi.com
Hepatitis C virus (HCV) is an important human pathogen with a high chronicity rate. An
estimated 71 million people worldwide are living with chronic hepatitis C (CHC) infection …

[HTML][HTML] Progress in the development of preventive and therapeutic vaccines for hepatitis C virus

J Torresi, D Johnson, H Wedemeyer - Journal of hepatology, 2011 - Elsevier
Hepatitis C virus (HCV) is a blood borne disease estimated to chronically infect 3% of the
worlds' population causing significant morbidity and mortality. Current medical therapy is …