Next-generation bNAbs for HIV-1 cure strategies

AI Schriek, YLT Aldon, MJ van Gils, SW de Taeye - Antiviral research, 2023 - Elsevier
Despite the ability to suppress viral replication using anti-retroviral therapy (ART), HIV-1
remains a global public health problem. Curative strategies for HIV-1 have to target and …

[HTML][HTML] High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es …

GM Bwire, BG Aiko, IH Mosha, MS Kilapilo… - Scientific Reports, 2023 - nature.com
To curb HIV infection rate in Tanzania, antiretroviral therapy (ART) has been scaled up since
2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line …

HIV-1 Transmission Cluster in Injection Drug Users in Nairobi City, Kenya

SK Webale, M Kilongosi, G Munyekenye… - Ethiopian Journal of …, 2023 - ajol.info
BACKGROUND: While there is a striking increase in the prevalence of HIV in injection drug
users, information on envelope-gene subtypes and transmission clusters in injection drug …

Investigating Alignment-Free Machine Learning Methods for HIV-1 Subtype Classification

KE Wade, L Chen, C Deng, G Zhou… - Bioinformatics …, 2024 - academic.oup.com
Motivation Many viruses are organized into taxonomies of subtypes based on their genetic
similarities. For human immunodeficiency virus 1 (HIV-1), subtype classification plays a …

[PDF][PDF] Revealing Novel Antiretroviral Candidate from Garcinia mangostana L. againts HIV-1 Infection via Reverse Transcriptase Inhibition: In Silico Study

VD Kharisma, ANM Ansori, AAA Murtadlo… - Research Journal of …, 2024 - researchgate.net
Human immunodeficiency virus (HIV) is a genus of Lentivirus that triggers opportunistic
diseases in the human body. HIV-1 has been a major problem for the world community for a …

Molecular phylogenetics of HIV-1 subtypes in African populations: a case study of Sub-Saharan African countries

HO Obura, CD Mlay, L Moyo, BM Karumbo, KM Omar… - bioRxiv, 2022 - biorxiv.org
Despite advances in antiretroviral therapy that have revolutionized HIV-1 disease
management, effective control of the HIV-1 infection pandemic remains elusive. Increased …

[PDF][PDF] George M. Bwire, Beatrice Godwin Aiko 3, 4, Idda H. Mosha 5, Mary S. Kilapilo 2, Alli Mangara 6, Patrick Kazonda 6, Janeth P. Swai 7, Omary Swalehe 7 …

AM Vandamme - Scientific Reports, 2023 - run.unl.pt
To curb HIV infection rate in Tanzania, antiretroviral therapy (ART) has been scaled up since
2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line …

Host CCR5 and HIV-1 env/pol Polymorphisms: Role in transmission and virulence in the Kenyan population

GC Langat, R Biegon, WG Mbuthia… - African Journal of Health …, 2023 - ajol.info
RESULTS A total of 74 articles were screened and 66 eligible articles were reviewed, four
(4) of them touching on the origin and evolutionary mechanisms of the human …

Recent Development on HIV Variants and HIV Vaccine

R Balatif, FH Harahap, ID Almira - Cermin Dunia Kedokteran, 2022 - cdkjournal.com
Human immunodeficiency virus (HIV) is a virus from the Retrovirus family that attacks human
immune cells, especially T lymphocytes. The increasing number of HIV cases requires a …

Pre-clinical development of chimeric virus-like particles based HPV: HIV vaccines by using mammalian cell expression system: limitations and challenges

CW Chen - 2022 - diposit.ub.edu
[eng] HPV and HIV-1 are important public health issues in some developing and
industrialized countries, but an effective chimeric HPV: HIV preventive vaccine is still …