Various roles of intestinal flora in the gut-brain axis response pathway have received
enormous attention because of their unique position in intestinal flora-derived metabolites …

Overeating ranges in severity from casual overindulgence to an overwhelming drive to
consume certain foods. At its most extreme, overeating can manifest as clinical diagnoses …

Despite progress in understanding the pathological mechanisms underlying psychiatric
disorders, translation from animal models into clinical use remains a significant bottleneck …

Rates of obesity and obesity-associated diseases have increased dramatically in countries
with developed economies. Substance use disorders (SUDs) are characterized by the …

Habits have garnered significant interest in studies of associative learning and maladaptive
behavior. However, habit research has faced scrutiny and challenges related to the …

Binge eating is a characteristic symptom observed in obese individuals that is related to
dysfunction of dopaminergic neurons (DNs). Intermittent administration of a high-fat diet …

Background Highly palatable food triggers behavioral responses including strong
motivation. These effects involve the reward system and dopamine neurons, which modulate …

Addiction is characterized by continued drug use despite negative consequences. In an
animal model, a subset of rats continues to self-administer cocaine despite footshock …

Neuropsychiatric symptoms (NPS) affect people with dementia (PwD) almost universally
across all stages of the disease, and regardless of its exact etiology. NPS lead to disability …

Food addiction (FA) is characterized by behavioral changes related to the consumption of
palatable foods, marked by dependence, impulsivity, and compulsion. Children and …