The paradoxical role of cytokines and chemokines at the tumor microenvironment: a comprehensive review

T Abdul-Rahman, S Ghosh, SM Badar, A Nazir… - European Journal of …, 2024 - Springer
Tumor progression and eradication have long piqued the scientific community's interest.
Recent discoveries about the role of chemokines and cytokines in these processes have …

Role of Extracellular Vesicles in Castration-Resistant Prostate Cancer

C Liao, Z Huang, J Liu, M Deng, L Wang… - Critical Reviews in …, 2024 - Elsevier
Prostate cancer (PCa) is a common health threat to men worldwide, and castration-resistant
PCa (CRPC) is the leading cause of PCa-related deaths. Extracellular vesicles (EVs) are …

Luteolin inhibits A549 cells proliferation and migration by down-regulating androgen receptors

X Li, Y Tang, P Liang, M Sun, T Li, Z Shen… - European Journal of …, 2023 - Springer
Abstract Background Yi Fei Qing Hua Granules (YQG) is a traditional Chinese herbal
medicine with the effects of inhibiting the proliferation of lung cancer cells. Luteolin is one of …

[HTML][HTML] An assessment of the (anti) androgenic properties of hexachloronaphthalene (HxCN) in male rats

J Stragierowicz, M Nasiadek, O Stasikowska-Kanicka… - Chemosphere, 2024 - Elsevier
The persistent organic pollutants (POPs) defined by the Stockholm Convention include
polychlorinated naphthalenes (PCNs); of these, the most toxic, persistent, abundant, dioxin …

An integrative evaluation of circadian gene TIMELESS as a pan-cancer immunological and predictive biomarker

Y Yang, X Tang, Z Lin, T Zheng, S Zhang, T Liu… - European Journal of …, 2023 - Springer
Background The gene TIMELESS, which is involved in the circadian clock and the cell cycle,
has recently been linked to various human cancers. Nevertheless, the association between …

Adiponcosis interplay: adipose tissue, microenvironment and prostate cancer

E Di Zazzo, B Barone, F Crocetto - Journal of Basic and Clinical …, 2024 - degruyter.com
The word “Adiponcosis,” surfaced in 2013 from the fusion of the two words “adiposis” and
“oncosis”, was introduced to highlight the complex and multifactorial relationship between …

The key roles of thyroid hormone in mitochondrial regulation, at interface of human health and disease

S Sagliocchi, F Restolfer, A Cossidente… - Journal of Basic and …, 2024 - degruyter.com
Mitochondria are highly plastic and dynamic organelles long known as the powerhouse of
cellular bioenergetics, but also endowed with a critical role in stress responses and …

ZNF692 promotes cell proliferation, invasion and migration of human prostate cancer cells by targeting the EMT signaling pathway

H Chen, Y Li, G Wu, Q Zeng, H Huang… - European Journal of …, 2024 - Springer
Background Prostate cancer poses a considerable threat to human health. At present, the
mechanism of tumor progression remains unclear. ZNF692 is overexpressed in many …

Deiodination and tumor progression: the interplay between thyroid hormones intracellular activation and the androgen signal

S Sagliocchi, L Acampora… - Journal of Basic and …, 2023 - degruyter.com
Thyroid hormones (THs, T3 and T4) are diffuse endocrine factors that regulate the growth,
differentiation and metabolism of many cells and tissues. Due to their pleiotropic actions …

The intricate role of glutamine in pathophysiological contexts

A Nappi, C Miro - Journal of Basic and Clinical Physiology and …, 2023 - degruyter.com
Glutamine is one of the most abundant nonessential amino acids in the bloodstream and
contributes to virtually every biosynthetic pathway in proliferating cells, taking on an …