Neurobiologic Advances from the Brain Disease Model of Addiction | New England Journal of
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An increasing number of research studies over the last three decades suggest that a wide
range of substance and process addictions may serve similar functions. The current article …

Introduction: Despite known sex differences in the endocannabinoid system of animals, little
attention has been paid to sex differences in human's cannabis use patterns and effects. The …

BACKGROUND: This study aims to estimate general and racial-ethnic specific cumulative
probability of developing dependence among nicotine, alcohol, cannabis or cocaine users …

The word 'addiction'these days is used to refer to a chronic condition where there is an
unhealthily powerful motivation to engage in a particular behaviour. This can be driven by …

Objective: This is the first in a series ofinvestigations ofthe social consequences of
psychiatric disorders based on the National Comorbidity Survey. Data on the relationship …

OBJECTIVE: Epidemiological studies indicate that experimentation with addictive drugs and
onset of addictive disorders is primarily concentrated in adolescence and young adulthood …

The factors causing the transition from recreational drug consumption to addiction remain
largely unknown. It has not been tested whether dopamine (DA) is sufficient to trigger this …

Drugs of abuse cause persistent alterations in synaptic plasticity that may underlie addiction
behaviors. Evidence suggests glial cells have an essential and underappreciated role in the …

Background Current and comprehensive information on the epidemiology ofDSM-IV12-
month and lifetime drug use disorders in the United States has not been available …