Transfusion of hyperimmune plasma for protecting foals against Rhodococcus equi pneumonia

SK Kahn, ND Cohen, AI Bordin… - Equine veterinary …, 2023 - Wiley Online Library
The bacterium Rhodococcus equi causes pneumonia in foals that is prevalent at breeding
farms worldwide. In the absence of an effective vaccine, transfusion of commercial plasma …

Equine immunoglobulins and organization of immunoglobulin genes

S Walther, TV Rusitzka, US Diesterbeck… - Developmental & …, 2015 - Elsevier
Our understanding of how equine immunoglobulin genes are organized has increased
significantly in recent years. For equine heavy chains, 52 IGHV, 40 IGHD, 8 IGHJ and 11 …

[HTML][HTML] Vaccination with the recombinant major outer membrane protein elicits long-term protection in mice against vaginal shedding and infertility following a …

S Pal, MI Cruz-Fisher, C Cheng, JR Carmichael… - NPJ vaccines, 2020 - nature.com
Implementation of a vaccine is likely the best approach to curtail Chlamydia trachomatis
infections. The aim of this study was to determine the ability of a vaccine formulated with the …

Enhancement of the protective efficacy of a Chlamydia trachomatis recombinant vaccine by combining systemic and mucosal routes for immunization

P Ralli-Jain, D Tifrea, C Cheng, S Pal, LM De la Maza - Vaccine, 2010 - Elsevier
Chlamydia trachomatis causes respiratory and sexually transmitted infections. Here, we
tested a vaccine formulated with the recombinant major outer membrane protein from C …

Chromatographic purification of equine immunoglobulin GF (ab) 2 from plasma

A Fernandes, JO Kaundinya, G Daftary… - … of Chromatography B, 2008 - Elsevier
The antibody fragments generated from hyperimmune equine IgG is widely used as anti-
snake venom, anti-scorpion venom, anti-diphtheria, anti-tetanus, anti-gangrene and anti …

[HTML][HTML] Safety of equine tetanus antitoxin for prophylactic use in Ethiopia: a retrospective multi-center study

M Joseph, Y Woldeamanuel, G Medhin… - Tropical Medicine and …, 2023 - Springer
Background Tetanus remains a severe life-threatening infectious disease and neurological
disorder in many parts of the world, where immunization programs are suboptimal. Any …

Next-generation sequencing reveals new insights about gene usage and CDR-H3 composition in the horse antibody repertoire

TC Manso, M Groenner-Penna, JC Minozzo… - Molecular …, 2019 - Elsevier
Horse serum antibodies have been used for greater than a century for the treatment and
prophylaxis of infectious diseases and envenomations. Little is known, however, about the …

Purification of equine IgG using membrane based enhanced hybrid bioseparation technique: a potential method for manufacturing hyperimmune antibody

L Wang, X Sun, R Ghosh - Biotechnology and bioengineering, 2008 - Wiley Online Library
Hyperimmune equine IgG is widely used as antivenom and anti‐rabies agents. This article
discusses a membrane based enhanced hybrid bioseparation technique for efficient and …

[HTML][HTML] IgE and IgG epitope mapping by microarray peptide-immunoassay reveals the importance and diversity of the immune response to the IgG3 equine …

SG De-Simone, P Napoleão-Pêgo, LAL Teixeira-Pinto… - Toxicon, 2014 - Elsevier
The presence of whole horse IgG in therapeutic snake antivenom preparations of high purity
is a contamination that can cause IgE-mediated allergic reactions in patients. In this study …

Cascade ultrafiltration bioreactor-separator system for continuous production of F (ab′) 2 fragment from immunoglobulin G

L Wang, T Khan, K Mohanty, R Ghosh - Journal of membrane science, 2010 - Elsevier
We discuss a continuous two-stage cascade ultrafiltration bioreactor-separator system for
fragmentation of immunoglobulin G (IgG) by pepsin and purification of F (ab′) 2 fragment …