Long-term respiratory effects of mustard vesicants
Sulfur mustard and related vesicants are cytotoxic alkylating agents that cause severe
damage to the respiratory tract. Injury is progressive leading, over time, to asthma …
damage to the respiratory tract. Injury is progressive leading, over time, to asthma …
Targeting tumor necrosis factor alpha to mitigate lung injury induced by mustard vesicants and radiation
R Malaviya, JD Laskin, R Businaro… - Disaster medicine and …, 2023 - cambridge.org
Pulmonary injury induced by mustard vesicants and radiation is characterized by DNA
damage, oxidative stress, and inflammation. This is associated with increases in levels of …
damage, oxidative stress, and inflammation. This is associated with increases in levels of …
[HTML][HTML] Downregulation of miR‑29b‑3p promotes α‑tubulin deacetylation by targeting the interaction of matrix metalloproteinase‑9 with integrin β1 in nasal polyps
Z Liu, H Liu, D Yu, J Gao… - … Journal of Molecular …, 2021 - spandidos-publications.com
Abstract Matrix metalloproteinase (MMP)‑9 is a key enzyme responsible for extracellular
matrix degradation and contributes to the progressive histological changes observed in …
matrix degradation and contributes to the progressive histological changes observed in …
Repetitive diacetyl vapor exposure promotes ubiquitin proteasome stress and precedes bronchiolitis obliterans pathology
J Wang, SY Kim, E House, HM Olson, CJ Johnston… - Archives of …, 2021 - Springer
Bronchiolitis obliterans (BO) is a devastating lung disease seen commonly after lung
transplant, following severe respiratory tract infection or chemical inhalation exposure …
transplant, following severe respiratory tract infection or chemical inhalation exposure …
Single-cell resolution of human airway epithelial cells exposed to bronchiolitis obliterans-associated chemicals
CY Chu, SY Kim, GS Pryhuber… - … of Physiology-Lung …, 2024 - journals.physiology.org
Bronchiolitis obliterans (BO) is a fibrotic lung disease characterized by progressive luminal
narrowing and obliteration of the small airways. In the nontransplant population, inhalation …
narrowing and obliteration of the small airways. In the nontransplant population, inhalation …
The immunomodulatory effects of mesenchymal stem cells on long term pulmonary complications in an animal model exposed to a sulfur mustard analog
Abstract Introduction Sulfur Mustard (SM) is one of the most lethal chemicals with major
complications manifested in the lungs. Although the pathogenesis behind SM-induced lung …
complications manifested in the lungs. Although the pathogenesis behind SM-induced lung …
Exogenous mesenchymal stem cells affect the function of endogenous lung stem cells (club cells) in phosgene-induced lung injury
K Ye, D He, Y Shao, N Xu, C Jin, L Zhang… - … and biophysical research …, 2019 - Elsevier
Exogenous mesenchymal stem cells (MSCs) affect lung cells via cytokines as well as
vesicles and activate the Notch signaling pathway thus affecting the proliferation of …
vesicles and activate the Notch signaling pathway thus affecting the proliferation of …
Mesenchymal Stem Cell Therapy Mitigates Acute and Chronic Lung Damages of Sulfur Mustard Analog Exposure
M Tapak, S Sadeghi, T Ghazanfari… - Iranian Journal of …, 2024 - ijaai.tums.ac.ir
Sulfur mustard (SM) is an established chemical weapon that can result in severe damage to
parts of the body. Currently, there are no effective treatments available for SM-caused …
parts of the body. Currently, there are no effective treatments available for SM-caused …
Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats
RC Rancourt, JS Rioux, LA Veress… - Drug and chemical …, 2019 - Taylor & Francis
Methyl isocyanate (MIC) is a highly toxic industrial chemical causing acute lethality after
inhalation. The objective of this study was to determine whether alterations in hemostasis …
inhalation. The objective of this study was to determine whether alterations in hemostasis …
Diacetyl inhalation impairs airway epithelial repair in mice infected with influenza A virus
MD McGraw, M Yee, SY Kim… - … of Physiology-Lung …, 2022 - journals.physiology.org
Bronchiolitis obliterans (BO) is a debilitating disease of the small airways that can develop
following exposure to toxic chemicals as well as respiratory tract infections. BO development …
following exposure to toxic chemicals as well as respiratory tract infections. BO development …