The function of vascular endothelial growth factor (VEGF) in cancer is not limited to
angiogenesis and vascular permeability. VEGF-mediated signalling occurs in tumour cells …

The neuropilins (Nrps) are multifunctional proteins involved in development, immunity and
cancer. Neuropilin-1 (Nrp1), or its homologue neuropilin-2 (Nrp2), are coreceptors that …

Abstract Nerve-glia (NG2) glia or oligodendrocyte precursor cells (OPCs) are distributed
throughout the gray and white matter and generate myelinating cells. OPCs in white matter …

The ability to differentiate human pluripotent stem cells into endothelial cells with properties
of cord-blood endothelial colony–forming cells (CB-ECFCs) may enable the derivation of …

Epstein–Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and
nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal …

Vascular endothelial growth factor-B (VEGF-B), discovered over 15 years ago, has long
been seen as one of the more ambiguous members of the VEGF family. VEGF-B is produced …

Plexin transmembrane receptors and their semaphorin ligands, as well as their co-receptors
(Neuropilin, Integrin, VEGFR2, ErbB2, and Met kinase) are emerging as key regulatory …

The gut microbiota influences intestinal barrier integrity through mechanisms that are
incompletely understood. Here we show that the commensal microbiota weakens the …

Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the
vascular system, exert trophic effects on neural cells during development and adulthood …

The sharing of molecules function that affects both tumor growth and neoangiogenesis with
cells of the immune system creates a mutual interplay that impairs the host's immune …