[HTML][HTML] An unsupervised cluster-based feature grouping model for early diabetes detection

MM Hassan, S Mollick, F Yasmin - Healthcare Analytics, 2022 - Elsevier
Diabetes mellitus is often a hyperglycemic condition that poses a substantial threat to human
health. Early diabetes detection decreases morbidity and mortality. Due to the scarcity of …

Reactive oxygen species in biological media are they friend or foe? Major In vivo and In vitro sensing challenges

MA Cardoso, HMR Gonçalves, F Davis - Talanta, 2023 - Elsevier
Abstract The role of Reactive Oxygen Species (ROS) on biological media has been shifting
over the years, as the knowledge on the complex mechanism that lies in underneath their …

[HTML][HTML] Mitigating diabetes associated with reactive oxygen species (ROS) and protein aggregation through pharmacological interventions

G Bennici, H Almahasheer, M Alghrably, D Valensin… - RSC …, 2024 - pubs.rsc.org
Diabetes mellitus, a complex metabolic disorder, presents a growing global health
challenge. In 2021, there were 529 million diabetics worldwide. At the super-regional level …

[HTML][HTML] Biomarkers of oxidative stress in diabetes mellitus with diabetic nephropathy complications

P Goycheva, K Petkova-Parlapanska… - International Journal of …, 2023 - mdpi.com
The present study aimed to investigate and compare biomarkers of oxidative stress and the
activity of antioxidant enzymes in the plasma of patients with different stages of diabetic …

[HTML][HTML] Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic …

F Mehvari, F Imanparast, P Mohaghegh… - European Journal of …, 2023 - Springer
Background The oxidative modification of low density lipoprotein (LDL) is closely associated
with an increased risk for coronary artery disease (CAD) in diabetic patients. The purpose of …

[HTML][HTML] Pharmacological and Genetic Suppression of VDAC1 Alleviates the Development of Mitochondrial Dysfunction in Endothelial and Fibroblast Cell Cultures …

KN Belosludtsev, DA Serov, AI Ilzorkina, VS Starinets… - Antioxidants, 2023 - mdpi.com
Prolonged hyperglycemia related to diabetes and its complications leads to multiple cellular
disorders, the central one being the dysfunction of mitochondria. Voltage-dependent anion …

[HTML][HTML] Low-glucose culture environment can enhance the wound healing capability of diabetic adipose-derived stem cells

CW Li, TH Young, MH Wang, MY Pei, TY Hsieh… - Stem Cell Research & …, 2023 - Springer
Background Application of autologous adipose-derived stem cells (ASC) for diabetic chronic
wounds has become an emerging treatment option. However, ASCs from diabetic …

[HTML][HTML] Jatrorrhizine improves endothelial function in diabetes and obesity through suppression of endoplasmic reticulum stress

Y Zhou, Y Wang, CT Vong, Y Zhu, B Xu… - International Journal of …, 2022 - mdpi.com
Jatrorrhizine (JAT) is one of the major bioactive protoberberine alkaloids found in rhizoma
coptidis, which has hypoglycemic and hypolipidemic potential. This study aimed to evaluate …

Phytochemical Assessment and Evaluation of the Anti-Oxidant, Anti-Microbial, Anti-Cholesterol, and Anti-Diabetic Activities of Triumphetta Pentandra Methanol Based …

RJ Mwalimu, ASB Packirisamy - Journal of Inorganic and Organometallic …, 2023 - Springer
The study aimed at the determination of phytoconstituents in Triumphetta pentandra leaf
extract and evaluated its in vitro antioxidant, antimicrobial, anticholesterol, and anti-diabetic …

Apigenin alleviates diabetic endothelial dysfunction through activating AMPK/PI3K/Akt/eNOS and Nrf2/HO‐1 signaling pathways

L Miao, MS Cheong, C Zhou, M Farag… - Food …, 2023 - Wiley Online Library
Abstract Apigenin (4′, 5, 7‐trihydroxyflavone) is a natural flavone reported to present anti‐
diabetic and anti‐oxidative bioactivities. The effect of apigenin to mitigate endothelial …