Background Alzheimer's disease (AD) is a progressive neurodegenerative disease that can
cause dementia. We aim to screen out the hub genes involved in AD based on microarray …

Ginkgo leaf is the most used form of supplement for cognitive ailments. The standardized
extract formulation EGb 761 is a dietary supplement with proven benefit in several …

Overexposure to manganese (Mn) has been known to induce neuronal death and
neurodegenerative symptoms. However, the precise mechanisms underlying Mn …

The incidence of cancer and Alzheimer's disease (AD) increases exponentially with age. A
growing body of epidemiological evidence and molecular investigations inspired the …

The amyloidogenic pathway is a prominent feature of Alzheimer's disease (AD). However,
growing evidence suggests that a linear disease model based on β‐amyloid peptide (Aβ) …

Objectives: Lead (Pb) is a neurotoxicant heavy metal ubiquitously present in the eco-system.
The precise mechanism by which Pb confers its deleterious effects on the cellular profile of …

The transcription factor p53, a widely accepted tumor suppressor, regulates the expression
of many oncogenes and their downstream signaling pathways, resulting in a series of …

The etiology of Alzheimer's disease (AD) has been intensively studied. However, little is
known about the molecular alterations in early-stage and late-stage AD. Hence, we …

Observational studies have shown inverse associations between neurological diseases,
particularly dementia, and subsequent cancer risk, but is unknown whether this association …

Zyxin is an adaptor protein recently identified as a novel regulator of the homeodomain‐
interacting protein kinase 2 (HIPK 2)‐p53 signaling in response to DNA damage. We …