Objective Skeletal muscle regeneration relies on muscle-specific, adult stem cells (MuSCs),
MuSC progeny, muscle progenitor cells (MPCs), and a coordinated myogenic program that …

Trichothecenes (TCT) are very common mycotoxins. While the effects of DON, the most
prevalent TCT, have been extensively studied, less is known about the effect of other …

Although pathways controlling ribosome activity have been described to regulate
chondrocyte homeostasis in osteoarthritis, ribosome biogenesis in osteoarthritis is …

Background Lead (Pb) is a persistent environmental neurotoxin and its exposure even in
minute quantities has been known to induce neuronal defects. The immature brain is …

Rocaglamide has been reported to sensitize several cell types to TRAIL-induced apoptosis.
In recent years, advances in synthetic techniques have led to generation of novel …

Introduction In addition to the well-known cartilage extracellular matrix-related expression of
Sox9, we demonstrated that chondrogenic differentiation of progenitor cells is driven by a …

Neonatal neuropsychiatric stress induces alterations in neurodevelopment that can lead to
irreversible damage to neuronal physiology, and social, behavioral, and cognitive skills. In …

The regulation of gene expression via protein translation is critical for growth, development,
and stress response. While puromycin-based techniques have been used to quantify protein …

BMP7 is a morphogen capable of counteracting the OA chondrocyte hypertrophic phenotype
via NKX3-2. NKX3-2 represses expression of RUNX2, an important transcription factor for …

Results: Early Sox9 knockdown severely inhibited chondrogenic differentiation weeks later.
Sox9 expression during the immediate early phase of ATDC5 chondrogenic differentiation …