Aggressive pituitary tumours and pituitary carcinomas
Although usually benign, anterior pituitary tumours occasionally exhibit aggressive
behaviour, with invasion of surrounding tissues, rapid growth, resistance to conventional …
behaviour, with invasion of surrounding tissues, rapid growth, resistance to conventional …
Biological and therapeutic implications of the tumor microenvironment in pituitary adenomas
Pituitary adenomas (PAs) are neoplasms derived from the endocrine cells of the anterior
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …
Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients
P Burman, J Trouillas, M Losa… - European journal of …, 2022 - academic.oup.com
Objective To describe clinical and pathological characteristics and treatment outcomes in a
large cohort of aggressive pituitary tumours (APT)/pituitary carcinomas (PC). Design …
large cohort of aggressive pituitary tumours (APT)/pituitary carcinomas (PC). Design …
Aggressive pituitary tumors and pituitary carcinomas: from pathology to treatment
P Burman, O Casar-Borota… - The Journal of …, 2023 - academic.oup.com
Aggressive pituitary tumors (APTs) and pituitary carcinomas (PCs) are heterogeneous with
regard to clinical presentation, proliferative markers, clinical course, and response to …
regard to clinical presentation, proliferative markers, clinical course, and response to …
Real-life efficacy and predictors of response to immunotherapy in pituitary tumors: a cohort study
MD Ilie, C Villa, T Cuny, C Cortet, G Assie… - European journal of …, 2022 - academic.oup.com
Objective After temozolomide failure, no evidence-based treatment is available for pituitary
carcinomas (PCs) and aggressive pituitary tumors (APTs). To date, only 12 cases treated …
carcinomas (PCs) and aggressive pituitary tumors (APTs). To date, only 12 cases treated …
Therapeutic targeting of the pituitary tumor microenvironment
MD Ilie, D De Alcubierre, AL Carretti… - Pharmacology & …, 2023 - Elsevier
The tumor microenvironment (TME), the complex environment in which tumors develop, has
been increasingly targeted for cancer treatment in recent years. Aggressive pituitary tumors …
been increasingly targeted for cancer treatment in recent years. Aggressive pituitary tumors …
Immunotherapy in aggressive pituitary tumors and carcinomas: a systematic review
MD Ilie, A Vasiljevic, E Jouanneau… - Endocrine-related …, 2022 - erc.bioscientifica.com
Once temozolomide has failed, there is no recommended treatment option for pituitary
carcinomas and aggressive pituitary tumors. Immune-checkpoint inhibitors (ICIs) represent …
carcinomas and aggressive pituitary tumors. Immune-checkpoint inhibitors (ICIs) represent …
Prevalence and clinical correlations of SF3B1 variants in lactotroph tumours
J Simon, LG Perez-Rivas, Y Zhao… - European journal of …, 2023 - academic.oup.com
Objective A somatic mutational hotspot in the SF3B1 gene was reported in lactotroph
tumours. The aim of our study was to examine the prevalence of driver SF3B1 variants in a …
tumours. The aim of our study was to examine the prevalence of driver SF3B1 variants in a …
[HTML][HTML] Efficacy of pembrolizumab in patients with pituitary carcinoma: report of four cases from a phase II study
N Majd, SG Waguespack, F Janku, S Fu… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Pituitary carcinoma is an aggressive tumor characterized by metastatic spread beyond the
sellar region. Symptoms can be debilitating due to hormonal excess and survival is poor …
sellar region. Symptoms can be debilitating due to hormonal excess and survival is poor …
Aggressive corticotroph tumors and carcinomas
H Lasolle, A Vasiljevic, E Jouanneau… - Journal of …, 2022 - Wiley Online Library
Pituitary tumors are generally benign, although in rare cases aggressive pituitary tumors
(APTs) and carcinomas present important diagnostic and therapeutic challenges and are …
(APTs) and carcinomas present important diagnostic and therapeutic challenges and are …