Microinjections of a dopamine D1 receptor antagonist into the ventral tegmental area block the expression of cocaine conditioned place preference in rats

E Galaj, M Manuszak, D Arastehmanesh… - Behavioural brain …, 2014 - Elsevier
Stimulation of dopamine (DA) D1 receptors in the ventral tegmental area (VTA) is involved in
primary rewards. In the current study we investigated whether VTA D1 receptor stimulation …

Effects of the GluN2B-selective antagonist Ro 63-1908 on acquisition and expression of methamphetamine conditioned place preference in male and female rats

JR Yates, HL Campbell, LL Hawley, MJ Horchar… - Drug and alcohol …, 2021 - Elsevier
Background Methamphetamine abuse has increased significantly in recent years. Currently,
there are no FDA-approved pharmacotherapies for the treatment of methamphetamine use …

Differential modulation of ventral tegmental area circuits by the nociceptin/orphanin FQ system

JR Driscoll, TL Wallace, KA Mansourian, WJ Martin… - ENeuro, 2020 - eneuro.org
The neuropeptide nociceptin/orphanin FQ (N/OFQ) can be released by stressors and is
associated with disorders of emotion regulation and reward processing. N/OFQ and its …

Differential effects of 5-HT2C receptor activation by WAY 161503 on nicotine-induced place conditioning and locomotor activity in rats

DJ Hayes, TM Mosher, AJ Greenshaw - Behavioural brain research, 2009 - Elsevier
RATIONALE: Numerous studies indicate a role for both the serotonin 2C receptor (5-HT2C)
and the nicotinic acetylcholine receptor in locomotion, reinforcement and motivated …

Stimulation of serotonin1B receptors induces conditioned place aversion and facilitates cocaine place conditioning in rats

L Cervo, M Rozio, C Ekalle-Soppo, F Carnovali… - …, 2002 - Springer
Heading Abstract Rationale. Changes in serotonin 1B (5-HT 1B) receptor function appear to
modify the reinforcing properties of cocaine, but the direction of this effect is not completely …

Intravenous cocaine induced‐activity and behavioural sensitization in norepinephrine‐, but not dopamine‐transporter knockout mice

AN Mead, BA Rocha, DM Donovan… - European Journal of …, 2002 - Wiley Online Library
Previously, it was reported that both norepinephrine transporter (NET) and dopamine
transporter (DAT) knockout (KO) mice were sensitive to the reinforcing effects of cocaine …

Inhibition of methylphenidate-induced gene expression in the striatum by local blockade of D1 dopamine receptors: interhemispheric effects

M Yano, JA Beverley, H Steiner - Neuroscience, 2006 - Elsevier
Psychostimulants change the function of cortico-basal ganglia circuits. Some of these effects
are mediated by altered gene regulation in projection neurons of the striatum which …

Shifts in the neurobiological mechanisms motivating cocaine use with the development of an addiction-like phenotype in male rats

WJ Lynch, A Bakhti-Suroosh, JM Abel, C Davis - Psychopharmacology, 2021 - Springer
Rationale The development of addiction is accompanied by a shift in the mechanisms
motivating cocaine use from nucleus accumbens (NAc) dopamine D 1 receptor (D 1 R) …

Effects of SCH‐23390 on dopamine D1 receptor occupancy and locomotion produced by intraaccumbens cocaine infusion

JL Neisewander, RA Fuchs, LE O'Dell, TV Khroyan - Synapse, 1998 - Wiley Online Library
This study examined the effects of both systemic and intraaccumbens administration of SCH‐
23390 in rats on dopamine D1 receptor occupancy and on locomotor activity produced by …

Dopamine D1 receptor antagonist reduces stimulant-induced conditioned place preferences and dopamine receptor supersensitivity

SM Gu, HJ Cha, SW Seo, JT Hong, J Yun - … -Schmiedeberg's Archives of …, 2020 - Springer
Repeated administration of stimulants induces conditioned place preference (CPP).
Dopamine receptor supersensitivity is developed in stimulant-induced CPP animals; …