[图书][B] Lutte antivectorielle et élimination de la trypanosomiase humaine africaine (THA) à gambiense: réunion conjointe d'experts FAO/OMS (Réunion en ligne) 5–6 …

World Health Organization - 2022 - books.google.com
Page 1 PROGRAMME DE LUTTE CO CONTRE lutte contre LA de Programme SOMOSE
AFRICAINE PLTA FAO-AIEA - OMS - UA PROMOUVOIR L'AGRICULTURE ET LA SANTÉ la …

A profile of research on the parasitic trypanosomatids and the diseases they cause

D Horn - PLoS neglected tropical diseases, 2022 - journals.plos.org
The parasitic trypanosomatids cause lethal and debilitating diseases, the leishmaniases,
Chagas disease, and the African trypanosomiases, with major impacts on human and …

[HTML][HTML] A comparative analysis of single-cell transcriptomic technologies in plants and animals

VR Netla, H Shinde, G Kumar, A Dudhate, JC Hong… - Current Plant …, 2023 - Elsevier
The development of sequencing methods has resulted in the investigation of many
unexplored research areas. Among the different sequencing methods, single-cell …

Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing

EM Briggs, F Rojas, R McCulloch, KR Matthews… - Nature …, 2021 - nature.com
Developmental steps in the trypanosome life-cycle involve transition between replicative
and non-replicative forms specialised for survival in, and transmission between, mammalian …

Natural-product-based solutions for tropical infectious diseases

O Adegboye, MA Field, A Kupz, S Pai… - Clinical microbiology …, 2021 - Am Soc Microbiol
About half of the world's population and 80% of the world's biodiversity can be found in the
tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by …

Profiling the bloodstream form and procyclic form Trypanosoma brucei cell cycle using single-cell transcriptomics

EM Briggs, CA Marques, GR Oldrieve, J Hu, TD Otto… - Elife, 2023 - elifesciences.org
African trypanosomes proliferate as bloodstream forms (BSFs) and procyclic forms in the
mammal and tsetse fly midgut, respectively. This allows them to colonise the host …

The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands

S Hutchinson, S Foulon, A Crouzols, R Menafra… - PLoS …, 2021 - journals.plos.org
The long and complex Trypanosoma brucei development in the tsetse fly vector culminates
when parasites gain mammalian infectivity in the salivary glands. A key step in this process …

Functional insights from a surface antigen mRNA-bound proteome

L Melo do Nascimento, F Egler, K Arnold… - Elife, 2021 - elifesciences.org
Trypanosoma brucei is the causative agent of human sleeping sickness. The parasites'
variant surface glycoprotein (VSG) enables them to evade adaptive immunity via antigenic …

A sticky situation: When trypanosomatids attach to insect tissues

ML Povelones, NA Holmes, M Povelones - PLoS Pathogens, 2023 - journals.plos.org
Transmission of trypanosomatids to their mammalian hosts requires a complex series of
developmental transitions in their insect vectors, including stable attachment to an insect …

Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei

E Doleželová, M Kunzová, M Dejung, M Levin… - PLoS …, 2020 - journals.plos.org
Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life
cycle because the insect stage utilizes a cost-effective oxidative phosphorylation (OxPhos) …