Objective: To assess the efficacy and safety of whole-cell and acellular pertussis vaccines
administered to children singly or within diphtheria, tetanus and pertussis (DTP) vaccines …

Despite a high vaccine coverage, pertussis has re-emerged and has become the most
prevalent vaccine preventable disease in developed countries. The re-emergence of …

High titres of pertussis toxin (PT) antibody have been shown to be predictive of recent
infection with Bordetella pertussis. The seroprevalence of standardized anti-PT antibody …

The performance of four acellular pertussis vaccines containing between two and five
pertussis antigens combined with diphtheria and tetanus toxoids was compared with that of …

The prevalence of asthma and allergic disease has increased in many countries, and there
has been speculation that immunization promotes allergic sensitization. Bordetella pertussis …

Objective: To assess the reported rate of local reactions after administration of acellular
pertussis vaccine (DTPa) according to dose number and type of pertussis vaccine (whole …

The immunogenicity and reactogenicity of booster vaccination with GSK Biologicals'
hexavalent DTPa-HBV-IPV/Hib vaccine was assessed in toddlers aged 12–18 months …

Sustained high incidence of pertussis, particularly amongst unvaccinated infants, is of
concern. Inclusion of pertussis vaccination with tetanus and low dose diphtheria (Td) …

The widespread use of whole-cell pertussis vaccines in the second half of the 20th century
have reduced the incidence of the disease significantly. However, in some countries …

The safety and reactogenicity of a booster dose of GSK Biologicals' hexavalent DTPa-HBV-
IPV/Hib vaccine (N= 4725) was compared with the separate administration of GSK …