Are the epigenetic changes predictive of therapeutic efficacy for psychiatric disorders? A translational approach towards novel drug targets
V Micale, M Di Bartolomeo, S Di Martino, T Stark… - Pharmacology & …, 2023 - Elsevier
The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …
Emerging therapeutic potential of cannabidiol (CBD) in neurological disorders: a comprehensive review
Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its
potential therapeutic applications. This thorough analysis explores the increasing …
potential therapeutic applications. This thorough analysis explores the increasing …
Tetrahydrocannabinol and cannabidiol medicines for chronic pain and mental health conditions
Abstract Combination tetrahydrocannabinol (THC)/cannabidiol (CBD) medicines or CBD-
only medicines are prospective treatments for chronic pain, stress, anxiety, depression, and …
only medicines are prospective treatments for chronic pain, stress, anxiety, depression, and …
Quality of life and a surveillant endocannabinoid system
RA de Melo Reis, AR Isaac, HR Freitas… - Frontiers in …, 2021 - frontiersin.org
The endocannabinoid system (ECS) is an important brain modulatory network. ECS
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …
Cannabidiol: bridge between antioxidant effect, cellular protection, and cognitive and physical performance
G Jîtcă, BE Ősz, CE Vari, CM Rusz, A Tero-Vescan… - Antioxidants, 2023 - mdpi.com
The literature provides scientific evidence for the beneficial effects of cannabidiol (CBD), and
these effects extend beyond epilepsy treatment (eg, Lennox–Gastaut and Dravet …
these effects extend beyond epilepsy treatment (eg, Lennox–Gastaut and Dravet …
[HTML][HTML] Prospects for the use of cannabinoids in psychiatric disorders
M Graczyk, M Łukowicz, T Dzierzanowski - Frontiers in psychiatry, 2021 - frontiersin.org
Increasing evidence suggests an essential role of the endocannabinoid system in
modulating cognitive abilities, mood, stress, and sleep. The psychoactive effects of cannabis …
modulating cognitive abilities, mood, stress, and sleep. The psychoactive effects of cannabis …
Phytocannabinoids and schizophrenia: Focus on adolescence as a critical window of enhanced vulnerability and opportunity for treatment
The recent shift in socio-political debates and growing liberalization of Cannabis use across
the globe has raised concern regarding its impact on vulnerable populations such as …
the globe has raised concern regarding its impact on vulnerable populations such as …
Individually tailored dosage regimen of full-spectrum Cannabis extracts for autistic core and comorbid symptoms: a real-life report of multi-symptomatic benefits
PSS Montagner, W Medeiros, LCR da Silva… - Frontiers in …, 2023 - frontiersin.org
Autism Spectrum Disorders (ASD) may significantly impact the well-being of patients and
their families. The therapeutic use of cannabis for ASD has gained interest due to its …
their families. The therapeutic use of cannabis for ASD has gained interest due to its …
Binge-like alcohol exposure in adolescence: behavioural, neuroendocrine and molecular evidence of abnormal neuroplasticity… and return
A Brancato, V Castelli, G Lavanco, G Tringali, V Micale… - Biomedicines, 2021 - mdpi.com
Binge alcohol consumption among adolescents affects the developing neural networks
underpinning reward and stress processing in the nucleus accumbens (NAc). This study …
underpinning reward and stress processing in the nucleus accumbens (NAc). This study …
Enhancing endocannabinoid control of stress with cannabidiol
The stress response is a well-defined physiological function activated frequently by life
events. However, sometimes the stress response can be inappropriate, excessive, or …
events. However, sometimes the stress response can be inappropriate, excessive, or …