Osteoclast-mediated bone resorption is responsible for bone metabolic diseases, negatively
impacting people's health and life. It has been demonstrated that microRNA influences the …

Diffuse idiopathic skeletal hyperostosis (DISH) is a condition characterized by the
calcification and ossification of the ligaments of the cervical spine; in some cases, it may …

Purpose: As the population ages, there is an increased risk of fracture and morbidity
diseases associated with aging, such as age-related osteoporosis and other bone diseases …

Bone remodeling and repair require osteogenic cells to reach the sites that need to be
rebuilt, indicating that stimulation of osteoblast migration could be a promising …

As a ubiquitous environmental pollutant, benzo [a] pyrene (BaP) has been extensively
studied for over 80 years. While much research has focused on its genotoxic and …

Osteoarthritis (OA), a chronic degenerative joint disease, is highly prevalent among the
aging population, and often leads to joint pain, disability, and a diminished quality of life …

Background MMP-9-dependent proteolysis of histone H3 N-terminal tail (H3NT) is an
important mechanism for activation of gene expression during osteoclast differentiation. Like …

Genetic risk factors for osteoporosis, a prevalent disease associated with aging, have been
examined in many genome wide association studies (GWASs). A major challenge is to …

Recent observations indicate that the cross-sectional area (CSA) of vertebral bodies is on
average 10% smaller in healthy newborn girls than in newborn boys, a striking difference …

Objective. The target of the present paper was to reveal the influence of LncRNA BC083743
on osteogenesis in human bone marrow mesenchymal stem cells (hBMSCs). Methods …