Selective breeding for physical inactivity produces cognitive deficits via altered hippocampal mitochondrial and synaptic function

NR Kerr, TJ Kelty, X Mao, TE Childs… - Frontiers in Aging …, 2023 - frontiersin.org
Physical inactivity is the 4th leading cause of death globally and has been shown to
significantly increase the risk for developing Alzheimer's Disease (AD). Recent work has …

Kv2 channels contribute to neuronal activity within the vagal afferent-nTS reflex arc

A Ramirez-Navarro, L Lima-Silveira… - … of Physiology-Cell …, 2024 - journals.physiology.org
Diversity in the functional expression of ion channels contributes to the unique patterns of
activity generated in visceral sensory A-type myelinated neurons versus C-type …

Enhancement of the Evoked Excitatory Transmission in the Nucleus Tractus Solitarius Neurons after Sustained Hypoxia in Mice Depends on A2A Receptors

JR Souza, L Lima-Silveira, D Accorsi-Mendonça… - Neuroscience, 2024 - Elsevier
The first synapses of the afferents of peripheral chemoreceptors are located in the Nucleus
Tractus Solitarius (NTS) and there is evidence that short-term sustained hypoxia (SH–24 h …

Oxytocin and corticotropin‐releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia

P Gama de Barcellos Filho, HA Dantzler… - The Journal of …, 2024 - Wiley Online Library
Chronic intermittent hypoxia (CIH) in rodents mimics the hypoxia‐induced elevation of blood
pressure seen in individuals experiencing episodic breathing. The brainstem nucleus tractus …

Chronic vagotomy induces nTS glial activation, reduced glutamatergic signaling, and blunted cardiorespiratory responses

GC Hofmann - 2024 - mospace.umsystem.edu
The brainstem nucleus tractus solitarii (nTS) is the first site of integration of viscerosensory
information provided by afferents of the vagus nerves. The nTS critically contributes to …