The tools for virulence of Cryptococcus neoformans

C Coelho, AL Bocca, A Casadevall - Advances in applied microbiology, 2014 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

Quantitative proteomic profiling of cerebrospinal fluid to identify candidate biomarkers for Alzheimer's disease

G Sathe, CH Na, S Renuse… - PROTEOMICS …, 2019 - Wiley Online Library
Purpose The aim of this study is to identify the potential cerebrospinal fluid (CSF) biomarkers
for Alzheimer's disease and to evaluate these markers on independent CSF samples using …

Proteomics of Cryptococcus neoformans: From the Lab to the Clinic

B Muselius, SL Durand, J Geddes-McAlister - International Journal of …, 2021 - mdpi.com
Fungal pathogens cause an array of diseases by targeting both immunocompromised and
immunocompetent hosts. Fungi overcome our current arsenal of antifungals through the …

Quantitative proteomic analysis of the frontal cortex in Alzheimer's disease

G Sathe, M Albert, J Darrow, A Saito… - Journal of …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by
intracellular formation of neurofibrillary tangles and extracellular deposition of β‐amyloid …

Quantitative Proteomic and Phosphoproteomic Analysis of H37Ra and H37Rv Strains of Mycobacterium tuberculosis

R Verma, SM Pinto, AH Patil, J Advani… - Journal of Proteome …, 2017 - ACS Publications
Mycobacterium tuberculosis, the causative agent of tuberculosis, accounts for 1.5 million
human deaths annually worldwide. Despite efforts to eradicate tuberculosis, it still remains a …

Proteomic and phosphoryproteomic investigations reveal that autophagy-related protein 1, a protein kinase for autophagy initiation, synchronously deploys …

HY Lin, JL Ding, YJ Peng, MG Feng, SH Ying - Msystems, 2022 - Am Soc Microbiol
Autophagy is a conserved intracellular degradation mechanism in eukaryotes and is
initiated by the protein kinase autophagy-related protein 1 (Atg1). However, except for the …

Quantitative phosphoproteomic analysis of IL‐33‐mediated signaling

SM Pinto, RS Nirujogi, PL Rojas, AH Patil… - …, 2015 - Wiley Online Library
Interleukin‐33 (IL‐33) is a novel member of the IL‐1 family of cytokines that plays diverse
roles in the regulation of immune responses. IL‐33 exerts its effects through a heterodimeric …

Phosphoproteomic profiling reveals Epstein-Barr virus protein kinase integration of DNA damage response and mitotic signaling

R Li, G Liao, RS Nirujogi, SM Pinto, PG Shaw… - PLoS …, 2015 - journals.plos.org
Epstein-Barr virus (EBV) is etiologically linked to infectious mononucleosis and several
human cancers. EBV encodes a conserved protein kinase BGLF4 that plays a key role in the …

Analysis of the Candida albicans phosphoproteome

SD Willger, Z Liu, RA Olarte, ME Adamo… - Eukaryotic …, 2015 - Am Soc Microbiol
Candida albicans is an important human fungal pathogen in both immunocompetent and
immunocompromised individuals. C. albicans regulation has been studied in many contexts …

Phosphoproteome Analysis Links Protein Phosphorylation to Cellular Remodeling and Metabolic Adaptation during Magnaporthe oryzae Appressorium Development

WL Franck, E Gokce, SM Randall, Y Oh… - Journal of proteome …, 2015 - ACS Publications
The rice pathogen, Magnaporthe oryzae, undergoes a complex developmental process
leading to formation of an appressorium prior to plant infection. In an effort to better …