Background Psychiatric disorders are multigenic diseases with complex etiology that
contribute significantly to human morbidity and mortality. Although clinically distinct, several …

Depression is a frequent mood disorder that might impair the brain-gut axis. In this study, we
divided 30 mice into five groups: untreated mice, mice with depression-like behaviors, mice …

Nitrosative stress, as an important oxygen metabolism disorder, has been shown to be
closely associated with cardiovascular diseases, such as myocardial ischemia/reperfusion …

It is widely held that schizophrenia involves an active process of peripheral inflammation that
induces or reflects brain inflammation with activation of microglia, the brain's resident …

Risk variants for schizophrenia affect more than 100 genomic loci, yet cell-and tissue-
specific roles underlying disease liability remain poorly characterized. We have generated …

Aim Over the past several decades, there has been a growing research interest in the role of
inflammation in the pathogenesis of schizophrenia. This review aims to summarize evidence …

The association between obsessive–compulsive disorder (OCD) and Tourette's/chronic tic
disorders (TD/CTD) with autoimmune diseases (ADs) is uncertain. In this nationwide study …

Functional magnetic resonance imaging (fMRI) studies in psychiatry use various tasks to
identify case‐control differences in the patterns of task‐related brain activation. Differently …

Gene expression levels vary across developmental stage, cell type, and region in the brain.
Genomic variants also contribute to the variation in expression, and some neuropsychiatric …

Psychotic disorders are common and disabling. Overlaps in clinical course in addition to
epidemiological and genetic associations raise the possibility that autoimmune mechanisms …