Plasmid transfer by conjugation in Gram-negative bacteria: from the cellular to the community level
Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …
The spread of antibiotic resistance genes in vivo model
S Tao, H Chen, N Li, T Wang… - Canadian Journal of …, 2022 - Wiley Online Library
Infections caused by antibiotic‐resistant bacteria are a major public health threat. The
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …
Virulence factors in coagulase-negative staphylococci
A França, V Gaio, N Lopes, LDR Melo - Pathogens, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …
Acquired antibiotic resistance genes: an overview
AHAM Van Hoek, D Mevius, B Guerra… - Frontiers in …, 2011 - frontiersin.org
In this review an overview is given on antibiotic resistance (AR) mechanisms with special
attentions to the AR genes described so far preceded by a short introduction on the …
attentions to the AR genes described so far preceded by a short introduction on the …
Diverse functions of restriction-modification systems in addition to cellular defense
K Vasu, V Nagaraja - Microbiology and molecular biology reviews, 2013 - Am Soc Microbiol
Restriction-modification (RM) systems are ubiquitous and are often considered primitive
immune systems in bacteria. Their diversity and prevalence across the prokaryotic kingdom …
immune systems in bacteria. Their diversity and prevalence across the prokaryotic kingdom …
Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi
The vast majority of bacteria, including human pathogens and microbiome species, lack
genetic tools needed to systematically associate genes with phenotypes. This is the major …
genetic tools needed to systematically associate genes with phenotypes. This is the major …
Bacteriophages and their genomes
GF Hatfull, RW Hendrix - Current opinion in virology, 2011 - Elsevier
Bacteriophages occupy a unique position in biology, representing an absolute majority of all
organisms in the biosphere. Because their genomes are relatively small, elucidating the …
organisms in the biosphere. Because their genomes are relatively small, elucidating the …
Evolutionary ecology of prokaryotic immune mechanisms
Bacteria have a range of distinct immune strategies that provide protection against
bacteriophage (phage) infections. While much has been learned about the mechanism of …
bacteriophage (phage) infections. While much has been learned about the mechanism of …
The discovery, mechanisms, and evolutionary impact of anti-CRISPRs
AL Borges, AR Davidson… - Annual review of …, 2017 - annualreviews.org
Bacteria and archaea use CRISPR-Cas adaptive immune systems to defend themselves
from infection by bacteriophages (phages). These RNA-guided nucleases are powerful …
from infection by bacteriophages (phages). These RNA-guided nucleases are powerful …
Type I restriction enzymes and their relatives
WAM Loenen, DTF Dryden, EA Raleigh… - Nucleic acids …, 2014 - academic.oup.com
Type I restriction enzymes (REases) are large pentameric proteins with separate restriction
(R), methylation (M) and DNA sequence-recognition (S) subunits. They were the first …
(R), methylation (M) and DNA sequence-recognition (S) subunits. They were the first …