Recent developments in age-related macular degeneration: a review

WM Al-Zamil, SA Yassin - Clinical interventions in aging, 2017 - Taylor & Francis
Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

[PDF][PDF] Mechanisms of age-related macular degeneration

J Ambati, BJ Fowler - Neuron, 2012 - cell.com
Age-related macular degeneration (AMD), a progressive condition that is untreatable in up
to 90% of patients, is a leading cause of blindness in the elderly worldwide. The two forms of …

[HTML][HTML] Vision loss after intravitreal injection of autologous “stem cells” for AMD

AE Kuriyan, TA Albini, JH Townsend… - … England Journal of …, 2017 - Mass Medical Soc
Adipose tissue–derived “stem cells” have been increasingly used by “stem-cell clinics” in the
United States and elsewhere to treat a variety of disorders. We evaluated three patients in …

Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye

Y Jia, ST Bailey, TS Hwang… - Proceedings of the …, 2015 - National Acad Sciences
Retinal vascular diseases are important causes of vision loss. A detailed evaluation of the
vascular abnormalities facilitates diagnosis and treatment in these diseases. Optical …

Quantitative optical coherence tomography angiography of choroidal neovascularization in age-related macular degeneration

Y Jia, ST Bailey, DJ Wilson, O Tan, ML Klein, CJ Flaxel… - Ophthalmology, 2014 - Elsevier
Purpose To detect and quantify choroidal neovascularization (CNV) in patients with age-
related macular degeneration (AMD) using optical coherence tomography (OCT) …

Age-related macular degeneration preferred practice pattern®

CJ Flaxel, RA Adelman, ST Bailey, A Fawzi, JI Lim… - …, 2020 - aaojournal.org
Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …

Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris …

I Bhutto, G Lutty - Molecular aspects of medicine, 2012 - Elsevier
There is a mutualistic symbiotic relationship between the components of the
photoreceptor/retinal pigment epithelium (RPE)/Bruch's membrane (BrMb)/choriocapillaris …

[HTML][HTML] IL-1 family members mediate cell death, inflammation and angiogenesis in retinal degenerative diseases

Y Wooff, SM Man, R Aggio-Bruce, R Natoli… - Frontiers in …, 2019 - frontiersin.org
Inflammation underpins and contributes to the pathogenesis of many retinal degenerative
diseases. The recruitment and activation of both resident microglia and recruited …

Spectral-domain optical coherence tomography angiography of choroidal neovascularization

TE de Carlo, MA Bonini Filho, AT Chin, M Adhi… - Ophthalmology, 2015 - Elsevier
Purpose To describe the characteristics as well as the sensitivity and specificity of detection
of choroidal neovascularization (CNV) on optical coherence tomography angiography …

Immunology of age-related macular degeneration

J Ambati, JP Atkinson, BD Gelfand - Nature Reviews Immunology, 2013 - nature.com
Age-related macular degeneration (AMD) is a leading cause of blindness in aged
individuals. Recent advances have highlighted the essential role of immune processes in …