[HTML][HTML] Long-noncoding RNAs as epigenetic regulators in neurodegenerative diseases

P Ruffo, F De Amicis, E Giardina… - Neural regeneration …, 2023 - journals.lww.com
The growing and rapid development of high-throughput sequencing technologies have
allowed a greater understanding of the mechanisms underlying gene expression regulation …

Thioredoxin-1 Rescues MPP+/MPTP-Induced Ferroptosis by Increasing Glutathione Peroxidase 4

L Bai, F Yan, R Deng, R Gu, X Zhang, J Bai - Molecular Neurobiology, 2021 - Springer
Abstract Parkinson's disease (PD), a common neurodegenerative disease, is typically
associated with the loss of dopaminergic neuron in the substantia nigra pars compacta …

Pin1-Catalyzed Conformation Changes Regulate Protein Ubiquitination and Degradation

J Jeong, M Usman, Y Li, XZ Zhou, KP Lu - Cells, 2024 - mdpi.com
The unique prolyl isomerase Pin1 binds to and catalyzes cis–trans conformational changes
of specific Ser/Thr-Pro motifs after phosphorylation, thereby playing a pivotal role in …

Electrochemical sensor based on reduced graphene oxide supported dumbbell-shaped CuCo2O4 for real-time monitoring of H2O2 released from cells

L Jiang, Y Zhao, P Zhao, S Zhou, Z Ji, D Huo… - Microchemical …, 2021 - Elsevier
Real-time monitoring of hydrogen peroxide (H 2 O 2) released from living tumor cells is still a
huge challenge. Herein, reduced graphene oxide supported dumbbell-shaped CuCo 2 O 4 …

Long non‐coding RNA NORAD functions as a microRNA‐204‐5p sponge to repress the progression of Parkinson's disease in vitro by increasing the solute carrier …

S Zhou, D Zhang, J Guo, Z Chen, Y Chen, J Zhang - IUBMB life, 2020 - Wiley Online Library
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Long
non‐coding RNAs have important regulatory values in various human diseases. Non …

[HTML][HTML] GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults

L Cheslow, M Byrne, JS Kopenhaver, L Iacovitti… - npj Parkinson's …, 2024 - nature.com
Mitochondrial dysfunction and reactive oxygen species (ROS) accumulation within the
substantia nigra pars compacta (SNpc) are central drivers of dopaminergic (DA) neuron …

[HTML][HTML] MiR-29a inhibits MPP+-Induced cell death and inflammation in Parkinson's disease model in vitro by potential targeting of MAVS

YL Yang, TK Lin, YH Huang - European journal of pharmacology, 2022 - Elsevier
Parkinson's disease (PD) primarily affects the motor system and is the second most common
age-related neurodegenerative disorder after Alzheimer's disease. Mitochondrial complex I …

Developmental exposure to Pb2+ induces transgenerational changes to zebrafish brain transcriptome

DN Meyer, EJ Crofts, C Akemann, K Gurdziel, R Farr… - Chemosphere, 2020 - Elsevier
Abstract Lead (Pb 2+) is a major public health hazard for urban children, with profound and
well-characterized developmental and behavioral implications across the lifespan. The …

Long noncoding RNA NORAD regulates MPP+-induced Parkinson's disease model cells

Q Song, Y Geng, Y Li, L Wang, J Qin - Journal of Chemical Neuroanatomy, 2019 - Elsevier
Abstract Background Long non-coding RNAs (lncRNAs) have been demonstrated to play
important roles in human diseases. Yet, the functions of lncRNAs in neurodegenerative …

The effects of neuronal cell differentiation on TRPM7, TRPM8 and TRPV1 channels in the model of Parkinson's disease

A Öz, Ö Çelik - Neurological research, 2022 - Taylor & Francis
ABSTRACT Transient Receptor Potential Melastatin-like 7 (TRPM7), Transient Receptor
Potential Melastatin-like 8 (TRPM8) and Transient Receptor Potential Vanilloid-like 1 …