[HTML][HTML] New developments in anti-malarial target candidate and product profiles

JN Burrows, S Duparc, WE Gutteridge… - Malaria journal, 2017 - Springer
A decade of discovery and development of new anti-malarial medicines has led to a
renewed focus on malaria elimination and eradication. Changes in the way new anti …

[HTML][HTML] Malaria medicines: a glass half full?

TNC Wells, RH Van Huijsduijnen… - Nature Reviews Drug …, 2015 - nature.com
Despite substantial scientific progress over the past two decades, malaria remains a
worldwide burden that causes hundreds of thousands of deaths every year. New, affordable …

[PDF][PDF] WHO guidelines for malaria, 3 June 2022

World Health Organization - 2022 - apps.who.int
This document is a PDF generated from the WHO Guidelines for malaria hosted on the
MAGICapp online platform: https://app. magicapp. org/#/guideline/6287. Each time the …

When and how to update systematic reviews: consensus and checklist

P Garner, S Hopewell, J Chandler, H MacLehose… - bmj, 2016 - bmj.com
Updating of systematic reviews is generally more efficient than starting all over again when
new evidence emerges, but to date there has been no clear guidance on how to do this. This …

[PDF][PDF] WHO guideline on health workforce development, attraction, recruitment and retention in rural and remote areas: web annexes

World Health Organization - 2021 - apps.who.int
WHO guideline on health workforce development, attraction, recruitment and retention in
rural and remote areas. Web Annexes ISBN 978-92-4-002424-3 (electronic version)© World …

[HTML][HTML] Dihydroartemisinin–piperaquine for the prevention of malaria in pregnancy

A Kakuru, P Jagannathan, MK Muhindo… - … England Journal of …, 2016 - Mass Medical Soc
Background Intermittent treatment with sulfadoxine–pyrimethamine is widely recommended
for the prevention of malaria in pregnant women in Africa. However, with the spread of …

Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study

MD Spring, JT Lin, JE Manning… - The Lancet Infectious …, 2015 - thelancet.com
Background Dihydroartemisinin-piperaquine has been adopted as first-line artemisinin
combination therapy (ACT) for multidrug-resistant Plasmodium falciparum malaria in …

[HTML][HTML] Pyronaridine–artesunate or dihydroartemisinin–piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised …

I Sagara, AH Beavogui, I Zongo, I Soulama… - The Lancet, 2018 - thelancet.com
Background Artemether–lumefantrine and artesunate–amodiaquine are used as first-line
artemisinin-based combination therapies (ACTs) in west Africa. Pyronaridine–artesunate …

[HTML][HTML] Antimalarial activity of plant metabolites

WH Pan, XY Xu, N Shi, SW Tsang… - International Journal of …, 2018 - mdpi.com
Malaria, as a major global health problem, continues to affect a large number of people each
year, especially those in developing countries. Effective drug discovery is still one of the …

[HTML][HTML] Safety, tolerability, and efficacy of repeated doses of dihydroartemisinin-piperaquine for prevention and treatment of malaria: a systematic review and meta …

J Gutman, S Kovacs, G Dorsey, A Stergachis… - The Lancet infectious …, 2017 - thelancet.com
Background Intermittent preventive treatment (IPT) for malaria is used in infants, children,
adults, and pregnant women. Dihydroartemisinin-piperaquine (DP) is an effective, well …