A milestone for palliative care and pain relief

R Horton - The Lancet, 2018 - thelancet.com
concentrations of piperaquine and cardiac effects. In the WANECAM study, 7
dihydroartemisinin–piperaquine was administered without first imposing a fast, providing …

Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a …

F Camponovo, CF Ockenhouse, C Lee… - BMC infectious …, 2019 - Springer
Background The only licensed malaria vaccine, RTS, S/AS01, has been developed for
morbidity-control in young children. The potential impact on transmission of deploying such …

Novel naphthyl based 1, 2, 4-trioxanes: Synthesis and in vivo efficacy in the Plasmodium yoelii nigeriensis in Swiss mice

M Karnatak, M Hassam, M Vanangamudi… - Bioorganic & Medicinal …, 2021 - Elsevier
Abstract A new series of 1, 2, 4-trioxanes 9a1-a4, 9b1-b4, 10–13 and 9c1-c4 were
synthesized and evaluated against multidrug-resistant Plasmodium yoelii nigeriensis in …

Malaria chemoprevention with monthly dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years in …

TK Kwambai, A Dhabangi, R Idro, R Opoka, S Kariuki… - Trials, 2018 - Springer
Background Children hospitalised with severe anaemia in malaria endemic areas in Africa
are at high risk of readmission or death within 6 months post-discharge. Currently, no …

New insight-guided approaches to detect, cure, prevent and eliminate malaria

S Kumar, R Kumari, R Pandey - Protoplasma, 2015 - Springer
New challenges posed by the development of resistance against artemisinin-based
combination therapies (ACTs) as well as previous first-line therapies, and the continuing …

[HTML][HTML] Adherence to Mass Drug Administration with Dihydroartemisinin–Piperaquine and Plasmodium falciparum Clearance in Southern Province, Zambia

TP Finn, TR Porter, H Moonga, K Silumbe… - The American Journal …, 2020 - ncbi.nlm.nih.gov
Mass drug administration (MDA) with artemisinin combination therapy is a potentially useful
tool for malaria elimination programs, but its success depends partly on drug effectiveness …

Design, characterization and antimalarial efficacy of PEGylated galactosylated nano lipid carriers of primaquine phosphate

UK Baruah, K Gowthamarajan… - Artificial cells …, 2018 - Taylor & Francis
This study was aimed to design and optimize primaquine phosphate (PQ) loaded
nanostructured lipid carriers (NLCs) using response surface methodology. The optimized …

Comparison of anti-malarial drug efficacy in the treatment of uncomplicated malaria in African children and adults using network meta-analysis

S Whegang Youdom, R Tahar, LK Basco - Malaria Journal, 2017 - Springer
Background Artemisinin-based combination therapy (ACT) and novel drug combinations are
available and used in African countries to treat uncomplicated malaria. Network meta …

Dihydroartemisinin‐piperaquine versus artesunate‐amodiaquine for treatment of malaria infection in pregnancy in Ghana: an open‐label, randomised, non‐inferiority …

J Osarfo, H Tagbor, M Cairns… - Tropical medicine & …, 2017 - Wiley Online Library
Objective To determine whether dihydroartemisinin‐piperaquine (DHA‐PPQ) is non‐inferior
to artesunate‐amodiaquine (ASAQ) for treating uncomplicated malaria infection in …

Recent advances in molecular mechanisms of anticancer natural products that target mitochondrial bioenergetics

FA Urra, S Fuentes-Retamal, C Palominos… - Studies in Natural …, 2021 - Elsevier
Although previously it was considered that cancer cells had high glycolysis and
mitochondrial impairment, recent evidence has revealed that several events during …