The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans

ID Jacobsen - Current Clinical Microbiology Reports, 2023 - Springer
Abstract Purpose of Review The fungus Candida albicans has evolved to live in close
association with warm-blooded hosts and is found frequently on mucosal surfaces of healthy …

Fungal feelings in the irritable bowel syndrome: the intestinal mycobiome and abdominal pain

I van Thiel, W de Jonge, R van den Wijngaard - Gut microbes, 2023 - Taylor & Francis
Although the gut microbiota consists of bacteria, viruses, and fungi, most publications
addressing the microbiota-gut-brain axis in irritable bowel syndrome (IBS) have a sole focus …

A synthetic peptide mimic kills Candida albicans and synergistically prevents infection

S Schaefer, R Vij, JL Sprague, S Austermeier… - Nature …, 2024 - nature.com
More than two million people worldwide are affected by life-threatening, invasive fungal
infections annually. Candida species are the most common cause of nosocomial, invasive …

Competitive fungal commensalism mitigates candidiasis pathology

JS Kralova, C Donic, B Dassa, I Livyatan, P Jansen… - bioRxiv, 2024 - biorxiv.org
The mycobiota are a critical part of the gut microbiome, but host-fungal interactions and
specific functional contributions of commensal fungi to host fitness remain incompletely …

Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB-mediated barrier protection

JL Sprague, TB Schille, S Allert, V Trümper… - Plos …, 2024 - journals.plos.org
The opportunistic fungal pathogen Candida albicans thrives on human mucosal surfaces as
a harmless commensal, but frequently causes infections under certain predisposing …

Characterizing the microbiota of cleft lip and palate patients: a comprehensive review

E Gershater, Y Liu, B Xue, MK Shin, H Koo… - Frontiers in cellular …, 2023 - frontiersin.org
Orofacial cleft disorders, including cleft lip and/or palate (CL/P), are one of the most
frequently-occurring congenital disorders worldwide. The health issues of patients with CL/P …

Interplay between host and Candida albicans during commensal gut colonization

AW Day, CA Kumamoto - PLoS Pathogens, 2023 - journals.plos.org
AU: Pleaseconfirmthatallheadinglevelsarerepre…. Mammals are naturally colonized AU: Pleasecheckwhetherthechangesmadeinthe…
with a diverse consortium of microbes composed of bacteria, fungi and other organisms …

Candida albicans and Candida glabrata: global priority pathogens

M Katsipoulaki, MHT Stappers… - Microbiology and …, 2024 - Am Soc Microbiol
SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Escherichia coli Nissle 1917 Antagonizes Candida albicans Growth and Protects Intestinal Cells from C. albicans-Mediated Damage

Y Rebai, L Wagner, M Gnaien, ML Hammer, M Kapitan… - Microorganisms, 2023 - mdpi.com
Candida albicans is a pathobiont of the gastrointestinal tract. It can contribute to the diversity
of the gut microbiome without causing harmful effects. When the immune system is …

Immunomodulatory Effects of the Pea Defensin Psd1 in the Caco-2/Immune Cells Co-Culture upon Candida albicans Infection

IV Bogdanov, SI Fateeva, AD Voropaev… - International Journal of …, 2023 - mdpi.com
Candidiasis is one of the most common fungal diseases that can pose a threat to life in
immunodeficient individuals, particularly in its disseminated form. Not only fungal invasion …