The chemopreventive effects of polyphenols and coffee, based upon a DMBA mouse model with microRNA and mTOR gene expression biomarkers

R Molnar, L Szabo, A Tomesz, A Deutsch, R Darago… - Cells, 2022 - mdpi.com
Polyphenols are capable of decreasing cancer risk. We examined the chemopreventive
effects of a green tea (Camellia sinensis) extract, polyphenol extract (a mixture of blackberry …

Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells

Y Zhang, L Tao, L Fan, Y Peng, K Yang, Y Zhao… - Scientific reports, 2015 - nature.com
Previous work has shown that gap junction intercellular communication (GJIC) enhances
cisplatin (Pt) toxicity in testicular tumor cells but decreases it in non-tumor testicular cells. In …

Meprin β expression modulates the interleukin‐6 mediated JAK2‐STAT3 signaling pathway in ischemia/reperfusion‐induced kidney injury

S Abousaad, F Ahmed, A Abouzeid… - Physiological …, 2022 - Wiley Online Library
Meprin metalloproteinases have been implicated in the pathophysiology of
ischemia/reperfusion (IR)‐induced kidney injury. Previous in vitro data showed that meprin β …

A mystery of a cup of coffee; an insight look by chemist

J Karpinska, R Świsłocka, W Lewandowski - BioFactors, 2017 - Wiley Online Library
Fruits, vegetables as well as processed food products of plant origin are a rich source of
beneficial for human health constituents. Among them the polyphenols constitute a large …

[PDF][PDF] Chlorogenic acid slows down proteinuria and renal fibrosis in 5/6-nephrectomized rats by anti-oxidation and inhibiting accumulation of extracellular matrix

J Lou, X Gu, Y Xing, J Cui, W Lv, Y Zhang - Int. J. Clin. Exp. Med, 2016 - e-century.us
Object: Chlorogenic acid (CA), a phenolic compound, was reported to have beneficial effect
on cisplatin induced acute kidney injury. The present study aimed to introduce 5/6 …

Aqueous Extract and Solvent Fractions of Hancornia speciosa Fruits, Rutin, and Chlorogenic Acid Attenuate the Edema, Inflammation, and Myonecrosis Caused by …

MAO Bitencourt, M Torres-Rêgo… - Revista Brasileira de …, 2024 - Springer
Snakebites are considered a neglected tropical disease in Brazil and 70% of cases of
envenomation are attributed to the genus Bothrops. The efficient therapy to treat patients is …

Yerba Mate Attenuates Oxidative Stress Induced Renal Cell Damage

H Ceylan, CA Acar, S Pehlivanoglu, S Yesilot - Journal of Herbal Medicine, 2023 - Elsevier
Introduction In this study, the protective effects of yerba mate aqueous extract, which is
widely used in traditional medicine, against hydrogen peroxide (H 2 O 2)-induced toxicity …

Pharmacological induction of kidney regeneration

E Gagliardini, A Benigni, N Perico - … Transplantation, Bioengineering and …, 2017 - Elsevier
The incidence of kidney disease is increasing worldwide, becoming one of the major public
health problems. Until recently, the kidney was considered an organ with a limited capacity …

Alleviation of doxorubicin-induced nephrotoxicity by Clerodendrum volubile leaf extract in Wistar rats: A preliminary study

OR Molehin - Journal of Herbmed Pharmacology, 2020 - herbmedpharmacol.com
Abstract Introduction: Doxorubicin (DOX), a well-known chemotherapeutic drug, has been
reported to induce numerous toxic side effects including renal toxicity. This preliminary study …

[HTML][HTML] Oral hydrogel microspheres were used for highly specific delivery of Steamed Codonopsis lanceolata to exert the protective effects on cisplatin-induced acute …

Y Li, W Li, J Hu, H Shi, Q Shen, S Wang, S Jiang… - Journal of Functional …, 2023 - Elsevier
Abstract Although Steamed Codonopsis lanceolata (SCL) has been shown to protect
against acute kidney injury (AKI), Its poor stability and susceptibility to decomposition in the …