Natural product-based nanoformulations for cancer therapy: Opportunities and challenges

D Kashyap, HS Tuli, MB Yerer, A Sharma, K Sak… - Seminars in cancer …, 2021 - Elsevier
Application of natural product-based nanoformulations for the treatment of different human
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …

Phytotherapeutics in cancer invasion and metastasis

B Salehi, P Zucca, M Sharifi‐Rad… - Phytotherapy …, 2018 - Wiley Online Library
Cancer is a multifactorial disease, and therefore, a multitarget approach is needed to face
the complex cancer biology, based on the combined use of different natural and synthetic …

A systematic review on the neuroprotective perspectives of beta‐caryophyllene

KC Machado, MT Islam, ES Ali, R Rouf… - Phytotherapy …, 2018 - Wiley Online Library
Beta (β)‐caryophyllene (BCAR) is a major sesquiterpene of various plant essential oils
reported for several important pharmacological activities, including antioxidant, anti …

Recent progress and new perspectives for diterpenoid biosynthesis in medicinal plants

Z Hu, X Liu, M Tian, Y Ma, B Jin, W Gao… - Medicinal Research …, 2021 - Wiley Online Library
Abstract Diterpenoids, including more than 18,000 compounds, represent an important class
of metabolites that encompass both phytohormones and some industrially relevant …

[HTML][HTML] Recent advances in improved anticancer efficacies of camptothecin nano-formulations: A systematic review

M Ghanbari-Movahed, T Kaceli, A Mondal, MH Farzaei… - Biomedicines, 2021 - mdpi.com
Camptothecin (CPT), a natural plant alkaloid, has indicated potent antitumor activities via
targeting intracellular topoisomerase I. The promise that CPT holds in therapies is restricted …

[HTML][HTML] A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species

D Kemboi, X Peter, M Langat, J Tembu - Molecules, 2020 - mdpi.com
The genus Euphorbia is one of the largest genera in the spurge family, with diversity in
range, distribution, and morphology. The plant species in this genus are widely used in …

[HTML][HTML] A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

HM Hashiesh, C Sharma, SN Goyal, B Sadek… - Biomedicine & …, 2021 - Elsevier
The endocannabinoid system (ECS), a conserved physiological system emerged as a novel
pharmacological target for its significant role and potential therapeutic benefits ranging from …

Quercetin-and rutin-based nano-formulations for cancer treatment: A systematic review of improved efficacy and molecular mechanisms

M Ghanbari-Movahed, A Mondal, MH Farzaei… - Phytomedicine, 2022 - Elsevier
Background Natural products, with incredible chemical diversity, have been widely studied
for their antitumor potential. Quercetin (QU) and quercetin glycoside (rutin), both …

[HTML][HTML] Advances on natural abietane, labdane and clerodane diterpenes as anti-cancer agents: Sources and mechanisms of action

R Acquaviva, GA Malfa, MR Loizzo, J Xiao, S Bianchi… - Molecules, 2022 - mdpi.com
Extensive research over the past decades has identified numerous phytochemicals that
could represent an important source of anti-cancer compounds. There is an immediate need …

[HTML][HTML] Plant Secondary Metabolites with an Overview of Populus

A Movahedi, A Almasi Zadeh Yaghuti, H Wei… - International journal of …, 2021 - mdpi.com
Populus trees meet continuous difficulties from the environment through their life cycle. To
warrant their durability and generation, Populus trees exhibit various types of defenses …