The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment

I Falcão-Pires, AF Leite-Moreira - Heart failure reviews, 2012 - Springer
Diabetes mellitus is an important and prevalent risk factor for congestive heart failure.
Diabetic cardiomyopathy has been defined as ventricular dysfunction that occurs in diabetic …

Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure

GG Sokos, LA Nikolaidis, S Mankad, D Elahi… - Journal of cardiac …, 2006 - Elsevier
BACKGROUND: Insulin resistance is present in the setting of congestive heart failure.
Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and …

Diabetic cardiomyopathy: molecular mechanisms, detrimental effects of conventional treatment, and beneficial effects of natural therapy

B Parim, VV Sathibabu Uddandrao, G Saravanan - Heart Failure Reviews, 2019 - Springer
Diabetic complications are among the largely exigent health problems currently.
Cardiovascular complications, including diabetic cardiomyopathy (DCM), account for more …

Adaptation and maladaptation of the heart in diabetes: Part I: general concepts

H Taegtmeyer, P McNulty, ME Young - Circulation, 2002 - Am Heart Assoc
ular hypertrophy and increased heart mass, with mildly reduced left ventricular systolic
performance. 22 On the microscopic level, histological studies of autopsy and biopsy …

Insulin resistance and heart failure: molecular mechanisms

AR Aroor, CH Mandavia… - Heart failure clinics, 2012 - heartfailure.theclinics.com
Heart failure (HF) is a major cause of morbidity and mortality in the Western world. HF is
present in more than 5 million people in the United States, accounting for nearly US $40 …

Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated …

LA Nikolaidis, D Elahi, T Hentosz, A Doverspike… - Circulation, 2004 - Am Heart Assoc
Background—The failing heart demonstrates a preference for glucose as its metabolic
substrate. Whether enhancing myocardial glucose uptake favorably influences left …

Diabetes, left ventricular systolic dysfunction, and chronic heart failure

MR MacDonald, MC Petrie, NM Hawkins… - European heart …, 2008 - academic.oup.com
Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition
increases the likelihood of developing the other, and when they occur together in the same …

Renin-angiotensin system inhibition prevents type 2 diabetes mellitus: part 1. A meta-analysis of randomised clinical trials

AJ Scheen - Diabetes & metabolism, 2004 - Elsevier
Most individuals with arterial hypertension or congestive heart failure are insulin-resistant
and at a higher risk of developing type 2 diabetes (T2DM). The inhibition of the renin …

Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …