[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

[HTML][HTML] Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma

A Elmusrati, J Wang, CY Wang - International journal of oral science, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is
characterized by high morbidity and low survival rates with limited therapeutic options …

Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen …

C Tu, H Lu, T Zhou, W Zhang, L Deng, W Cao, Z Yang… - Biomaterials, 2022 - Elsevier
The diabetic wound is easily to develop into a chronic wound because of the extremely
serious and complex inflammatory microenvironment including biofilm formation, over …

[HTML][HTML] Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …

[HTML][HTML] Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy

AA Bhat, P Yousuf, NA Wani, A Rizwan… - Signal transduction and …, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …

[HTML][HTML] A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer

H Schinke, E Shi, Z Lin, T Quadt, G Kranz, J Zhou… - Molecular Cancer, 2022 - Springer
Background Epidermal growth factor receptor (EGFR) is both a driver oncogene and a
therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] Caspase 3 and cleaved caspase 3 expression in tumorogenesis and its correlations with prognosis in head and neck cancer: a systematic review and meta …

FFV Silva, ME Padín-Iruegas, VCA Caponio… - International journal of …, 2022 - mdpi.com
Head and neck cancer (HNC) is an ascending and agressive disease. The search for new
molecular markers is emerging to solve difficulties in diagnosis, risk management, prognosis …

[HTML][HTML] Cancer stem cell plasticity–a deadly deal

AP Thankamony, K Saxena, R Murali… - Frontiers in molecular …, 2020 - frontiersin.org
Intratumoral heterogeneity is a major ongoing challenge in the effective therapeutic targeting
of cancer. Accumulating evidence suggests that a fraction of cells within a tumor termed …

[HTML][HTML] Tumor microenvironment in head and neck squamous cell carcinoma: Functions and regulatory mechanisms

G Wang, M Zhang, M Cheng, X Wang, K Li, J Chen… - Cancer letters, 2021 - Elsevier
The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …

Tumor immune microenvironment in head and neck cancers

SMY Chen, AL Krinsky, RA Woolaver… - Molecular …, 2020 - Wiley Online Library
Head and neck cancers are a heterogeneous group of tumors that are highly aggressive
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …