Epigenetic alterations, including DNA methylation, play crucial roles in the tumor. Epigenetic
drugs like DNA methyltransferase-1 (DNMT1) inhibitors have been exhibited positive effects …

Simple Summary Tumors are not composed of a uniform ball of cells, but rather, a complex
set of diverse cells. Unfortunately, most transcriptomic techniques analyze the entire tumor …

Ethnopharmacological relevance Antrodia salmonea (AS), linked to the genus
Taiwanofungus, is a medicinal fungus, and exhibits anti-inflammatory, anti-oxidant, and …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type,
has often an aggressive course and is poorly responsive to current therapeutic approaches …

Oral cancer is a common malignancy worldwide, with high disease-related death rates. Oral
squamous cell carcinoma (OSCC) accounts for more than 90% of oral tumors, with surgical …

Similarly to other types of malignant tumours, the incidence of head and neck cancer is
increasing globally. It is frequently associated with smoking and alcohol abuse, and in a …

Introduction In this study, we investigate the role of radiomics for prediction of overall survival
(OS), locoregional recurrence (LRR) and distant metastases (DM) in stage III and IV HNSCC …

In recent years, to treat a diverse array of cancer forms, considerable advancements have
been achieved in the field of cancer immunotherapies. However, these therapies encounter …

Tumor development and progression hinge upon ongoing coevolution and crosstalk with the
tumor microenvironment. In particular, fibroblasts in the tumor stroma are coopted to support …

Tumor-associated macrophages (TAMs) play crucial roles in tumor progression and immune
responses. However, mechanisms of driving TAMs to antitumor function remain unknown …